Cellular uptake of pH/reduction responsive phosphorylcholine micelles
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DOI: 10.1039/c7nj02484c
Abstract: Phosphorylcholine micelles based on pH/reduction responsive copolymers, poly(e-caprolactone)-ss-b-poly((N,N-diethylaminoethyl methacrylate)-r-poly(2-methacryloyloxyethyl phosphorylcholine)) (PCL-ss-PDEAPMPC) were developed for the intracellular delivery of doxorubicin. The micelles were spherical (less than 90 nm in diameter) and demonstrated pH/reduction sensitivity. The DOX… read more here.
Keywords: reduction; cellular uptake; drug; reduction responsive ... See more keywords