Articles with "phosphorylmethyl pyrrolidines" as a keyword



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One-Pot Synthesis of N-(Phosphorylmethyl)Pyrrolidines via Acid-Catalyzed Cascade Elimination/Cyclization/Friedel–Crafts Reaction

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Published in 2020 at "Chemistry of Heterocyclic Compounds"

DOI: 10.1007/s10593-020-02697-2

Abstract: The efficient approach to novel water-soluble 2-aryl-substituted N-(phosphorylmethyl)pyrrolidines via acid-catalyzed elimination/cyclization/Friedel–Crafts reaction sequence of {[(4,4-diethoxybutyl)amino]methyl}phosphonates is proposed. Zwitterionic structure of N-(phosphorylmethyl) pyrrolidines has been proved by X-ray crystallography. read more here.

Keywords: phosphorylmethyl pyrrolidines; elimination cyclization; cyclization friedel; pyrrolidines via ... See more keywords