PHOTACs enable optical control of protein degradation
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DOI: 10.1126/sciadv.aay5064
Abstract: We present a modular approach to control the small molecule–mediated degradation of cellular proteins of interest using light. PROTACs (PROteolysis TArgeting Chimeras) are bifunctional molecules that target proteins for ubiquitylation by an E3 ligase complex… read more here.
Keywords: control protein; degradation; photacs enable; control ... See more keywords