Photo‐Cross‐Linking between BrU and Pyrene Residues in an RNA/DNA Hybrid
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202100626
Abstract: In this study, we investigated the photoreaction of BrU in a pyrene‐labeled DNA duplex, RNA duplex, and DNA/RNA hybrids. We found that the photoreactivity of BrU changed dramatically from hydrogen abstraction to cross‐linking by changing… read more here.
Keywords: dna; bru pyrene; cross linking; cross ... See more keywords
The Influence of Vanillin Acrylate Derivative on the Phase Separation Temperature of Environmental Photo-Cross-Linked N-isopropylacrylamide Copolymer and Hydrogel Thin Films
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Polymers and the Environment"
DOI: 10.1007/s10924-020-01793-w
Abstract: The present study emphasizes the fabrication of thermal and pH-responsive photo-cross-linked polymers and hydrogel thin films. N-isopropylacrylamide was used as a thermal responsive monomer, while a new pH-responsive monomer was synthesized based on vanillin 2-((dimethylamino)methyl)-4-formyl-6-methoxyphenyl… read more here.
Keywords: photo cross; hydrogel thin; thin films; cross linked ... See more keywords
Extraction of intrinsic cross-linking effects of A hard domains on segmental motion of B soft block for ABA triblock copolymer-based elastomers by utilizing photo cross-linking
Sign Up to like & getrecommendations! Published in 2020 at "Polymer"
DOI: 10.1016/j.polymer.2020.122343
Abstract: Abstract We here shed light on effects of the A domain cross-linking for the physical properties, especially for the B middle block segmental motion, of ABA triblock copolymers with a soft B block and A… read more here.
Keywords: photo cross; block; segmental motion; cross ... See more keywords
Extraction of intrinsic effects of glassy domain cross-linking on the tensile properties of ABA block copolymer elastomers via photo cross-linking approach
Sign Up to like & getrecommendations! Published in 2021 at "Polymer"
DOI: 10.1016/j.polymer.2021.124235
Abstract: Abstract Chemical or physical cross-links into the A glassy domains have been reported to enhance mechanical properties for glassy-b-soft-b-glassy ABA triblock copolymer-based elastomers. However, no reports dealt with the pure effects of the domain cross-linking,… read more here.
Keywords: photo cross; domain cross; tensile properties; cross ... See more keywords
Multifunctional Photo-Cross-Linking Probes: From Target Protein Searching to Imaging Applications.
Sign Up to like & getrecommendations! Published in 2022 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.2c00505
Abstract: ConspectusDespite advances in genome sequencing technology, the complete molecular interaction networks reflecting the biological functions of gene products have not been fully elucidated due to the lack of robust molecular interactome profiling techniques. Traditionally, molecular… read more here.
Keywords: multifunctional photo; cross linking; photo cross; cross ... See more keywords
Conditional Chaperone-Client Interactions Revealed by Genetically Encoded Photo-cross-linkers.
Sign Up to like & getrecommendations! Published in 2017 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.6b00647
Abstract: The cell envelope is an integral and essential component of Gram-negative bacteria. As the front line during host-pathogen interactions, it is directly challenged by host immune responses as well as other harsh extracellular stimuli. The… read more here.
Keywords: photo cross; cross linkers; client; protein ... See more keywords
Gold Nanoparticle-Based Photo-Cross-Linking Strategy for Cellular Target Identification of Supercomplex Molecular Systems.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04652
Abstract: Cellular target identification plays an essential role in innovative drug development and pharmacological mechanism elucidation. However, very few practical experimental methodologies have been developed for identifying target proteins for supercomplex molecular systems such as biologically… read more here.
Keywords: cellular target; supercomplex molecular; molecular systems; cross ... See more keywords
Exo-Enzymatic Cell-Surface Glycan Labeling for Capturing Glycan-Protein Interactions through Photo-Cross-Linking.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00043
Abstract: Tools to interrogate glycoconjugate-protein interactions in the context of living cells are highly attractive for the identification of critically important functional binding partners of glycan-binding proteins. These interactions are challenging to study due to the… read more here.
Keywords: cell surface; cross linking; cross; photo cross ... See more keywords
Quantitative Validation and Application of the Photo-Cross-Linking Selection for Double-Stranded DNA-Encoded Libraries.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00421
Abstract: The DNA-encoded compound library (DEL) technology has accelerated the target hits discovery in new drug development. While affinity-based DEL selection can distinguish high-affinity ligands, moderate-affinity ligands are also potential drug candidates with further modifications. Herein,… read more here.
Keywords: dna; affinity; cross linking; photo cross ... See more keywords
Tough Photo-Cross-Linked PCL-Hydroxyapatite Composites for Bone Tissue Engineering.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c01584
Abstract: Acrylate-based photo-cross-linked poly(ε-caprolactone) (PCL) tends to show low elongation and strength. Incorporation of osteo-inductive hydroxyapatite (HAp) further enhances this effect, which limits its applicability in bone tissue engineering. To overcome this, the thiol-ene click reaction… read more here.
Keywords: bone tissue; cross linked; tissue engineering; cross ... See more keywords
Fundamentals and Applications of Photo-Cross-Linking in Bioprinting.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.9b00812
Abstract: This review provides a detailed overview of the rapidly advancing field of biofabrication, particularly with regards to the use of photo-cross-linking (i.e., light-based) techniques. The major emphasis of this review is on the fundamentals of… read more here.
Keywords: photo cross; cross; linking bioprinting; fundamentals applications ... See more keywords