Exploring the photo-toxicity of hypoxic active iridium(III)-based sensitizers in 3D tumor spheroids.
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DOI: 10.1021/jacs.9b07723
Abstract: Among all molecules developed for anticancer therapies, photodynamic therapeutic agents have a unique profile. Their maximal activity is specifically triggered in tumors by light and toxicity of even systemically delivered drug is prevented in non-illuminated… read more here.
Keywords: oxygen; toxicity; tumor spheroids; iii based ... See more keywords