Photocatalyst‐free, Visible Light Driven, Gold Promoted Suzuki Synthesis of (Hetero)biaryls
Sign Up to like & getrecommendations! Published in 2017 at "ChemCatChem"
DOI: 10.1002/cctc.201701436
Abstract: A visible‐light driven Suzuki cross‐coupling reaction was performed with colored and bench‐stable arylazosulfones in the presence of Ph3PAuCl (5 mol %) as the catalyst. The absence of a photocatalyst, along with the use of commercially available and… read more here.
Keywords: driven gold; visible light; free visible; gold promoted ... See more keywords
Photocatalyst-free visible light driven synthesis of (E)-vinyl sulfones from cinnamic acids and arylazo sulfones
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2020.151898
Abstract: Abstract A photocatalyst-free visible light mediated decarboxylative sulfono functionalization protocol has been explored for the synthesis of (E)-vinyl sulfones from cinnamic acids and bench-stable arylazo sulfones. The latter have been utilized as sulfonyl radical precursors… read more here.
Keywords: synthesis vinyl; visible light; vinyl; free visible ... See more keywords
Visible-Light-Induced Photocatalyst-Free Radical Trifluoromethylation.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02150
Abstract: An attractive, versatile, and operationally simple, visible-light-induced, transition-metal-free, photocatalyst-free, and oxidant-free trifluoromethylation has been demonstrated. Triflic anhydride (Tf2O), being inexpensive and readily available, was chosen as the radical trifluoromethyl source. Thianthrene was used as a… read more here.
Keywords: photocatalyst free; light induced; free radical; visible light ... See more keywords
Metal and Photocatalyst-Free Amide Synthesis via Decarbonylative Condensation of Alkynes and Photoexcited Nitroarenes.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c02513
Abstract: Depending on the intrinsic photoactivity of nitroarenes, we herein developed a practical Brønsted acid-catalyzed decarbonylative amide synthesis from alkynes and photoexcited nitroarenes without any metal or photocatalyst. This method exhibited compatibility with water and air,… read more here.
Keywords: alkynes photoexcited; photoexcited nitroarenes; metal photocatalyst; amide synthesis ... See more keywords
Visible-Light-Driven Photocatalyst-Free Multicomponent Reactions: Green Synthesis of Tetraketones as Potent Antiviral Agents through Virtual Screening, Molecular Docking, and MD Simulations
Sign Up to like & getrecommendations! Published in 2025 at "ACS Omega"
DOI: 10.1021/acsomega.4c10660
Abstract: Herein, we report a photocatalyst (PC)-free, visible-light (30 W LED)-driven green and sustainable synthesis of a series of functionalized tetraketones by a one-pot multicomponent reaction at room temperature. The ethanol-mediated reaction of variably substituted aromatic/heteroaromatic,… read more here.
Keywords: molecular docking; screening molecular; virtual screening; visible light ... See more keywords
Photocatalyst-free photochemical deuteration via H/D exchange with D2O
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-61641-0
Abstract: Deuterium labeling is increasingly important across scientific fields, from drug development to materials engineering, but current methods often require expensive catalysts. Here we demonstrate a simple, photocatalyst-free approach for incorporating deuterium into organic molecules using… read more here.
Keywords: via exchange; free photochemical; deuteration via; photochemical deuteration ... See more keywords
Photocatalyst-free visible light promoted E → Z isomerization of alkenes
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DOI: 10.1039/c9gc04303a
Abstract: A simple and green method of visible light driven photocatalytic E to Z isomerization of alkenes has been developed. A variety of (Z)-alkenes can be prepared in the presence of visible light, without any additional… read more here.
Keywords: isomerization alkenes; photocatalyst free; visible light; free visible ... See more keywords
Visible-light-induced photocatalyst-free C-3 functionalization of indoles with diethyl bromomalonate
Sign Up to like & getrecommendations! Published in 2020 at "Green Chemistry"
DOI: 10.1039/d0gc00292e
Abstract: A visible-light induced green and efficient method is developed for the synthesis of α-indolyl diethyl malonates. The reaction proceeds without any photocatalysts or ligands in a green solvent in a short time. Moreover, the reaction… read more here.
Keywords: light induced; diethyl bromomalonate; photocatalyst free; visible light ... See more keywords
A visible-light-induced photocatalyst-free approach for C-3 dicarbonyl coumarin production.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc02399c
Abstract: A mild and efficient visible-light-induced synthesis of C-3 dicarbonyl coumarins from 3-arylacetylene coumarins without a photocatalyst was reported. This iodide-mediated method exhibited broad substrate scope and good functional group tolerance, and a series of C-3… read more here.
Keywords: dicarbonyl; induced photocatalyst; light induced; visible light ... See more keywords
Photocatalyst-free visible-light triggered amination of benzo[c][1,2,5]thiadiazole: direct C-N bond formation from C(sp2)-H bond.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc05811a
Abstract: The photoredox amination of arene protocols mostly comprises photocatalyst-mediated transformations. Herein, we presented the photocatalyst-free, visible-light promoted, direct conversion of C(sp2)-H to C(sp2)-N method. Multipurpose benzothiadiazoles are used as model synthons and secondary amines as… read more here.
Keywords: photocatalyst free; free visible; visible light; amination ... See more keywords
Photoinduced C(sp3)-H functionalization via the photocatalyst-free hydrogen atom transfer pathway.
Sign Up to like & getrecommendations! Published in 2025 at "Chemical communications"
DOI: 10.1039/d5cc05422b
Abstract: The direct functionalization of aliphatic C-H bonds represents a significant advancement in chemical synthesis, offering an efficient and sustainable strategy for the rapid assembly and late-stage modification of complex molecules. Recently, photocatalyst-free, light-promoted C(sp3)-H functionalization,… read more here.
Keywords: sp3 functionalization; free hydrogen; hydrogen atom; functionalization ... See more keywords