A Photocleavable Amphiphilic Prodrug Self-Assembled Nanoparticles with Effective Anticancer Activity In Vitro
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DOI: 10.3390/nano9060860
Abstract: Accelerating degradation of prodrug is an effective strategy for improving the pharmacological action. A photocleavable amphiphilic prodrug of methotrexate-coumarin derivative-PEG conjugates (MTX-AMC-PEG) with photo-triggered breakage to release clinical drug under laser irradiation was fabricated and… read more here.
Keywords: amphiphilic prodrug; assembled nanoparticles; photocleavable amphiphilic; anticancer activity ... See more keywords