Regioselective synthesis of 3-trifluoromethyl 1,2,4-triazoles via photocycloaddition of sydnone with CF3CN.
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DOI: 10.1039/d2cc03928a
Abstract: A general and regioselective synthesis of 3-trifluoromethyl 1,2,4-triazoles has been achieved through photocycloaddition of sydnone with trifluoroacetonitrile. This method employed trifluoroacetaldehyde O-(aryl)oxime as the CF3CN precursor and tolerated various functional groups to furnish 3-trifluoromethyl 1,2,4-triazole… read more here.
Keywords: synthesis trifluoromethyl; trifluoromethyl triazoles; photocycloaddition sydnone; regioselective synthesis ... See more keywords