A new GSH-responsive prodrug of 5-aminolevulinic acid for photodiagnosis and photodynamic therapy of tumors.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.111582
Abstract: 5-Aminolevulinic acid (5-ALA) and its two ester derivatives (5-ALA-OMe and 5-ALA-OHex) have been approved for photodiagnosis and photodynamic therapy (PDT) of tumors in the clinical. However, their pharmacological activities are limited by their instability under… read more here.
Keywords: ala ome; aminolevulinic acid; photodynamic therapy; photodiagnosis photodynamic ... See more keywords
Simultaneous Photodiagnosis and Photodynamic Treatment of Metastatic Melanoma
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24173153
Abstract: Metastatic melanoma (MM) has a poor prognosis and is attributed to late diagnoses only when metastases has already occurred. Thus, early diagnosis is crucial to improve its overall treatment efficacy. The standard diagnostic tools for… read more here.
Keywords: simultaneous photodiagnosis; diagnosis; treatment; metastatic melanoma ... See more keywords