Dithionated Nucleobases as Effective Photodynamic Agents against Human Epidermoid Carcinoma Cells
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DOI: 10.1002/cmdc.201800148
Abstract: Sulfur‐substituted nucleobases (i.e., thiobases) are a prospective class of compounds for clinical and cosmetic topical phototherapies. Recent investigations of several thiobases have revealed the ultrafast and efficient population of reactive triplet states upon ultraviolet‐A (UVA)… read more here.
Keywords: human epidermoid; photodynamic agents; dithionated nucleobases; epidermoid carcinoma ... See more keywords
Chemical antagonism between photodynamic agents and chemotherapeutics: mechanism and avoidance.
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DOI: 10.1039/c7cc07465d
Abstract: We report a photochemical reaction-induced antagonism between the photodynamic agent (PS) and anti-cancer drugs during combined therapy. The annihilation of singlet oxygen and alkene-containing drugs into inactive drug hydroperoxides is responsible for the antagonism, and… read more here.
Keywords: photodynamic agents; chemical antagonism; antagonism photodynamic; agents chemotherapeutics ... See more keywords