A hybrid biomaterial of biosilica and C-phycocyanin for enhanced photodynamic effect towards tumor cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.09.049
Abstract: Intricate mesoporous biosilica has many biomedical applications as a nanocarrier. However, its potential use in photodynamic therapy (PDT) has received little attention. This work reports the first fabrication of bio-engineered materials by covalently conjugating C-phycocyanin… read more here.
Keywords: photodynamic effect; biosilica; hybrid biomaterial; biomaterial biosilica ... See more keywords
Sustained photodynamic effect of single chirality-enriched single-walled carbon nanotubes
Sign Up to like & getrecommendations! Published in 2020 at "Carbon"
DOI: 10.1016/j.carbon.2020.02.002
Abstract: Abstract Semiconducting single-walled carbon nanotubes (s-SWNTs) are capable of fluorescence emission as well as photothermal and photodynamic actions, resulting from their near-infrared (NIR) absorptions corresponding to their S11 and S22 transitions. Here, we show that… read more here.
Keywords: carbon; walled carbon; carbon nanotubes; sustained photodynamic ... See more keywords
Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.837784
Abstract: The tumor-associated macrophage (TAM) serves as an immunosuppressive agent in the malignant tumor microenvironment, facilitating the development and metastasis of lung cancer. The photodynamic effect destabilizes cellular homeostasis owing to the generation of reactive oxygen… read more here.
Keywords: dna; damage; dna damage; photodynamic effect ... See more keywords
Enhanced Cellular Uptake and Photodynamic Effect with Amphiphilic Fluorinated Porphyrins: The Role of Sulfoester Groups and the Nature of Reactive Oxygen Species
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21082786
Abstract: A class of amphiphilic photosensitizers for photodynamic therapy (PDT) was developed. Sulfonate esters of modified porphyrins bearing—F substituents in the ortho positions of the phenyl rings have adequate properties for PDT, including absorption in the… read more here.
Keywords: oxygen; reactive oxygen; oxygen species; enhanced cellular ... See more keywords
Biological Evaluation of Photodynamic Effect Mediated by Nanoparticles with Embedded Porphyrin Photosensitizer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073588
Abstract: Clinically approved photodynamic therapy (PDT) is a minimally invasive treatment procedure that uses three key components: photosensitization, a light source, and tissue oxygen. However, the photodynamic effect is limited by both the photophysical properties of… read more here.
Keywords: evaluation; effect; nanoparticles embedded; photodynamic effect ... See more keywords