Tyrosinase-activated Nanocomposites for Double-modals Imaging Guided Photodynamic and Photothermal Synergistic Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300327
Abstract: Tyrosinase (TYR) is an important biomarker of melanoma. The exploration of fluorescent pr-obes-based composites is beneficial to build an integrative platform for the diagnosis and trea-tment of melanoma. Herein, we developed a multifunctional nanocomposite IOBOH@BSA… read more here.
Keywords: tyr; ioboh bsa; melanoma; photodynamic photothermal ... See more keywords
A Facile, Protein‐Derived Supramolecular Theranostic Strategy for Multimodal‐Imaging‐Guided Photodynamic and Photothermal Immunotherapy In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202109111
Abstract: Theranostic systems that permit both diagnosis and treatment in vivo are highly appealing means by which to meet the demands of precision medicine. However, most such systems remain subject to issues related to complex molecular… read more here.
Keywords: vivo; supramolecular theranostic; strategy; photodynamic photothermal ... See more keywords
Tailoring Multifunctional Small Molecular Photosensitizers to In Vivo Self-Assemble with Albumin to Boost Tumor-Preferential Accumulation, NIR Imaging, and Photodynamic/Photothermal/Immunotherapy.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202201298
Abstract: Cancer immunotherapy has great potential in tumor eradication and metastasis suppression. However, systemic administration of immune adjuvants and inadequate specificity in cancer treatment, lead to restricted therapeutic benefits and potential immune-related side effects in clinical… read more here.
Keywords: immunotherapy; imaging photodynamic; accumulation; photodynamic photothermal ... See more keywords
A pH-responsive zinc (II) metalated porphyrin for enhanced photodynamic/photothermal combined cancer therapy
Sign Up to like & getrecommendations! Published in 2019 at "Science China Materials"
DOI: 10.1007/s40843-019-9423-5
Abstract: The acidic tumor microenvironment is triggered by glycolysis in hypoxic condition, which can motivate the pH-responsive system to build certain triggers for efficiently tumor-targeted phototherapy. Additionally, the metalated porphyrin structures are widely studied in biomedical… read more here.
Keywords: therapy; responsive zinc; photodynamic photothermal; cancer ... See more keywords
IR780-dye loaded gold nanoparticles as new near infrared activatable nanotheranostic agents for simultaneous photodynamic and photothermal therapy and intracellular tracking by surface enhanced resonant Raman scattering imaging.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2018.02.007
Abstract: Due to the good transparency of the human tissue in the biological spectral window, near-infrared (NIR)-dye loaded nanosystems enable more effective light-activated therapy and better contrast imaging with major impact on nanomedicine. Herein, we prepare… read more here.
Keywords: gnp plu; photodynamic photothermal; ir780; plu ir780 ... See more keywords
Extended π-Conjugative Carbon Nitride for Single 1064 nm Laser-Activated Photodynamic/Photothermal Synergistic Therapy and Photoacoustic Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c22481
Abstract: The synergetic photodynamic/photothermal therapy, activated via a single-second near-infrared (NIR-II) laser and guided by photoacoustic imaging (PAI), receives significant attention for precise in vivo therapy. However, due to the lack of a corresponding theranostic agent,… read more here.
Keywords: photoacoustic imaging; therapy; 1064 laser; carbon nitride ... See more keywords
Construction of D-A-Conjugated Covalent Organic Frameworks with Enhanced Photodynamic, Photothermal, and Nanozymatic Activities for Efficient Bacterial Inhibition.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c05953
Abstract: Bacterial infection causes serious threats to human life, especially with the appearance of antibiotic-resistant bacteria. Phototherapeutic approaches have become promising due to their noninvasiveness, few adverse effects, and high efficiency. Herein, a covalent organic framework… read more here.
Keywords: bacterial inhibition; bdp; tapp bdp; efficient bacterial ... See more keywords
Exploring Low-Power Single-Pulsed Laser-Triggered Two-Photon Photodynamic/Photothermal Combination Therapy Using a Gold Nanostar/Graphene Quantum Dot Nanohybrid
Sign Up to like & getrecommendations! Published in 2023 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.3c03578
Abstract: Combined photodynamic/photothermal therapy (PDT/PTT) has emerged as a promising cancer treatment modality due to its potential synergistic effects and identical treatment procedures. However, its clinical application is hindered by long treatment times and complicated treatment… read more here.
Keywords: two photon; low power; graphene quantum; quantum dot ... See more keywords
Fe-TCPP@CS nanoparticles as photodynamic and photothermal agents for efficient antimicrobial therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials science"
DOI: 10.1039/d0bm01427c
Abstract: Traditional antimicrobial therapies always rely on antibiotics, which have led to the overuse of antibiotics and caused the emergence of multidrug-resistant (MDR) bacteria in recent years. In this study, an efficient and broad-spectrum antimicrobial system… read more here.
Keywords: tcpp nanoparticles; tcpp nps; photodynamic photothermal; nanoparticles photodynamic ... See more keywords
Multifunctional photodynamic/photothermal nano-agents for the treatment of oral leukoplakia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-022-01310-2
Abstract: Oral leukoplakia (OLK) has gained extensive attention because of the potential risk for malignant transformation. Photosensitizers (PSs) played an indispensable role in the photodynamic therapy (PDT) of OLK, but the poor light sensitivity greatly hampered… read more here.
Keywords: olk; multifunctional photodynamic; treatment; photodynamic photothermal ... See more keywords
Covalent organic polymer induces apoptosis of liver cancer cells via photodynamic and photothermal effects
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.986839
Abstract: The purpose of this study was to explore the photodynamic and photothermal effects of the supramolecular material Purp@COP and to test the anti-cancer effect on HepG2 cells in vitro. Materials and methods Purp@COP is a… read more here.
Keywords: photothermal effects; purp cop; photodynamic photothermal; covalent organic ... See more keywords