Kinetic Resolution of N-Allylic Pyrazoles via Photoexcited Chiral Copper Complex-Catalyzed Alkene E → Z Isomerization.
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DOI: 10.1021/acs.orglett.4c01220
Abstract: Herein, we present an efficient and practical kinetic resolution (KR) of racemic allylic pyrazoles utilizing photoexcited chiral-copper-complex-mediated alkene E → Z isomerization. This method enables the synthesis of both enantioenriched E- and Z-allylic pyrazoles, achieving… read more here.
Keywords: allylic pyrazoles; copper complex; alkene isomerization; photoexcited chiral ... See more keywords