Photoinduced Copper-Catalyzed C(sp3)-P Bond Formation by Coupling of Secondary Phosphines with N-(Acyloxy)phthalimides and N-Fluorocarboxamides.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00475
Abstract: A photoinduced copper-catalyzed C(sp3)-P bond formation has been developed by using N-(acyloxy)phthalimides as radical precursors and secondary phosphine boranes as coupling partners. A variety of alkyl carboxylic acid derivatives can be readily transformed into the… read more here.
Keywords: sp3 bond; formation; copper catalyzed; photoinduced copper ... See more keywords
Photoinduced, Copper-Catalyzed Radical Cross-Coupling of Cycloketone Oxime Esters, Alkenes, and Terminal Alkynes.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b01529
Abstract: A photoinduced, copper-catalyzed three-component radical cross-coupling of cycloketone oxime esters, alkenes, and terminal alkynes is described for the first time. Key to the success of this process was the integration of photoinduced iminyl radical-mediated C-C… read more here.
Keywords: radical cross; photoinduced copper; copper catalyzed; cross coupling ... See more keywords
Photoinduced Copper-Catalyzed Asymmetric C-O Cross-Coupling.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c06535
Abstract: The construction of carbon-heteroatom bonds is one of the most active areas of research in organic chemistry because the function of organic molecules is often derived from the presence of heteroatoms. Although considerable advances have… read more here.
Keywords: catalyzed asymmetric; copper catalyzed; copper; cross coupling ... See more keywords
Photoinduced, Copper-Catalyzed Enantioconvergent Alkylations of Anilines by Racemic Tertiary Electrophiles: Synthesis and Mechanism.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c12749
Abstract: Transition-metal catalysis of substitution reactions of alkyl electrophiles by nitrogen nucleophiles is beginning to emerge as a powerful strategy for synthesizing higher-order amines, as well as controlling their stereochemistry. Herein, we report that a readily… read more here.
Keywords: copper; racemic tertiary; mechanism; catalyzed enantioconvergent ... See more keywords
Photoinduced, Copper-Catalyzed Alkylation of Amines: A Mechanistic Study of the Cross-Coupling of Carbazole with Alkyl Bromides.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b07052
Abstract: We have recently reported that a variety of couplings of nitrogen, sulfur, oxygen, and carbon nucleophiles with organic halides can be achieved under mild conditions (-40 to 30 °C) through the use of light and… read more here.
Keywords: alkyl; copper; carb; cross coupling ... See more keywords
Photoinduced copper-catalysed asymmetric amidation via ligand cooperativity.
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03730-w
Abstract: The substitution of an alkyl electrophile by a nucleophile is a foundational reaction in organic chemistry that enables the efficient and convergent synthesis of organic molecules. Whereas substantial progress has been reported in recent years… read more here.
Keywords: catalysed asymmetric; copper; asymmetric amidation; substitution ... See more keywords
Photoinduced, copper-catalysed direct perfluoroalkylation of heteroarenes.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc02146c
Abstract: An efficient and general process is reported for the photoinduced, copper-catalysed direct perfluoroalkylation of C-H bonds in a broad range of heteroarenes with commercially available perfluoroalkyl iodides. This redox neutral process is simply based on… read more here.
Keywords: direct perfluoroalkylation; copper catalysed; photoinduced copper; catalysed direct ... See more keywords
Photoinduced copper-catalyzed enantioselective coupling reactions.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Society reviews"
DOI: 10.1039/d2cs00734g
Abstract: Copper-catalyzed enantioselective coupling has been widely investigated, which allows rapid construction of various chiral molecules. Despite important advances via polar and radical mechanisms, exploring general and practical strategies for the regio-, enantio- and diastereoselective assembly… read more here.
Keywords: copper; enantioselective coupling; copper catalyzed; photoinduced copper ... See more keywords
Photoinduced copper-catalyzed asymmetric radical three-component cross-coupling of 1,3-enynes with oxime esters and carboxylic acids
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00513e
Abstract: Catalytic radical difunctionalization of 1,3-enynes has recently been established as a potentially robust platform for construction of valuable allenes and propargylic compounds. Despite considerable advances made in the realm of... read more here.
Keywords: radical three; asymmetric radical; catalyzed asymmetric; three component ... See more keywords