Identification and characterization of a new class of (6-4) photolyase from Vibrio cholerae.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b00766
Abstract: Light is crucial for most of the organisms to perform many biological activities including vision, resetting of circadian rhythm, photosynthesis, and DNA repair. The Cryptochrome/Photolyase Family (CPF) represents an ancient group of UV-A/blue-light sensitive proteins… read more here.
Keywords: photolyase; dna repair; vibrio cholerae;
Structural changes within the bifunctional cryptochrome/photolyase CraCRY upon blue light excitation
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-45885-7
Abstract: Cryptochromes (CRYs) are an ubiquitously occurring class of photoreceptors, which are important for regulating the circadian rhythm of animals via a time-delayed transcription-translation feedback loop (TTFL). Due to their protein architecture and common FAD chromophore,… read more here.
Keywords: blue light; photolyase; structural changes; bifunctional cryptochrome ... See more keywords
Targeted Inactivation of DNA Photolyase Genes in Medaka Fish (Oryzias latipes)
Sign Up to like & getrecommendations! Published in 2017 at "Photochemistry and Photobiology"
DOI: 10.1111/php.12658
Abstract: Proteins of the cryptochrome/photolyase family (CPF) exhibit sequence and structural conservation, but their functions are divergent. Photolyase is a DNA repair enzyme that catalyzes the light‐dependent repair of ultraviolet (UV)‐induced photoproducts, whereas cryptochrome acts as… read more here.
Keywords: photolyase; dna photolyase; dependent repair; light dependent ... See more keywords
Structural and Functional Analysis of a Prokaryotic (6-4) Photolyase from the Aquatic Pathogen Vibrio Cholerae.
Sign Up to like & getrecommendations! Published in 2023 at "Photochemistry and photobiology"
DOI: 10.1111/php.13783
Abstract: Photolyases are flavoproteins, which are able to repair UV-induced DNA lesions in a light-dependant manner. According to their substrate, they can be distinguished as CPD- and (6-4) photolyases. While CPD-photolyases repair the predominantly occurring cyclobutane… read more here.
Keywords: vibrio cholerae; prokaryotic photolyases; prokaryotic photolyase; photolyase ... See more keywords
A putative bifunctional CPD/ (6-4) photolyase from the cyanobacteria Synechococcus sp. PCC 7335 is encoded by a UV-B inducible operon: New insights into the evolution of photolyases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.981788
Abstract: Photosynthetic organisms are continuously exposed to solar ultraviolet radiation-B (UV-B) because of their autotrophic lifestyle. UV-B provokes DNA damage, such as cyclobutane pyrimidine dimers (CPD) or pyrimidine (6-4) pyrimidone photoproducts (6-4 PPs). The cryptochrome/photolyase family… read more here.
Keywords: cpd; cyanobacteria synechococcus; bifunctional cpd; pcc 7335 ... See more keywords
The Gain and Loss of Cryptochrome/Photolyase Family Members during Evolution
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13091613
Abstract: The cryptochrome/photolyase (CRY/PL) family represents an ancient group of proteins fulfilling two fundamental functions. While photolyases repair UV-induced DNA damages, cryptochromes mainly influence the circadian clock. In this study, we took advantage of the large… read more here.
Keywords: family members; cryptochrome photolyase; cry; photolyase ... See more keywords