Precise Two-Photon Photodynamic Therapy using an Efficient Photosensitizer with Aggregation-Induced Emission Characteristics.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced materials"
DOI: 10.1002/adma.201701076
Abstract: Two-photon photodynamic therapy (PDT) is able to offer precise 3D manipulation of treatment volumes, providing a target level that is unattainable with current therapeutic techniques. The advancement of this technique is greatly hampered by the… read more here.
Keywords: photon; photodynamic therapy; photosensitizer aggregation; two photon ... See more keywords
Carrier-free core-shell nanodrugs for synergistic two-photon photodynamic therapy of cervical cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2018.09.095
Abstract: Carrier-free nanodrugs named BCNPs were prepared by the coassembly of 2,5-bis(4-(diethylamino)benzylidene)cyclopentanone (BDBC) and curcumin (CCM) in the absence of surfactants. The as-synthesized BCNPs possess high dispersity and stability in aqueous media, along with favorable photostability… read more here.
Keywords: photodynamic therapy; two photon; photon photodynamic; carrier free ... See more keywords
Thermosensitive nanocomposite gel for intra‐tumoral two‐photon photodynamic therapy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2019.01.019
Abstract: Abstract We propose here a new approach to achieve intratumoral near‐infrared (NIR) two‐photon photodynamic therapy (PDT). We established a composite micellar thermosensitive hydrogel made of clinically approved methoxy poly(ethylene glycol)‐polylactide copolymer (mPEG‐PDLLA) and Pluronic (F127).… read more here.
Keywords: photodynamic therapy; two photon; photon photodynamic; rheology ... See more keywords
A mitochondria-localized iridium(iii) photosensitizer for two-photon photodynamic immunotherapy against melanoma
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d2sc06675k
Abstract: Conventional photodynamic therapy mainly causes a therapeutic effect on the primary tumor through the localized generation of reactive oxygen species, while metastatic tumors remain poorly affected. Complementary immunotherapy is effective in eliminating small, non-localized tumors… read more here.
Keywords: two photon; photon photodynamic; melanoma; immunotherapy ... See more keywords