Synthesis and Characterization of Photoactivatable Doxycycline Analogues Bearing Two‐Photon‐Sensitive Photoremovable Groups Suitable for Light‐Induced Gene Expression
Sign Up to like & getrecommendations! Published in 2018 at "ChemBioChem"
DOI: 10.1002/cbic.201700628
Abstract: We report the synthesis and photolytic properties of caged 9‐aminodoxycycline derivatives modified with 2‐{4′‐bis‐[2‐(2methoxyethoxy)ethyl]‐4‐nitrobiphenyl‐3‐yl}prop‐1‐oxy (EANBP) and PEG7‐ylated (7‐diethylamino‐2‐oxo‐2H‐chromen‐4‐yl)methyl (PEG7‐DEACM) groups. 9‐Aminodoxycycline is a tetracycline analogue capable of activating transcription through the inducible TetOn transgene expression… read more here.
Keywords: photon sensitive; photon; two photon; light induced ... See more keywords