Allosteric Regulation of Rod Photoreceptor Phosphodiesterase 6 (PDE6) Elucidated by Chemical Cross-Linking and Quantitative Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2019.07.035
Abstract: Photoreceptor phosphodiesterase (PDE6) is the central effector enzyme in the visual excitation pathway in rod and cone photoreceptors. Its tight regulation is essential for the speed, sensitivity, recovery and adaptation of visual signaling. The rod… read more here.
Keywords: photoreceptor phosphodiesterase; phosphodiesterase pde6; cross; rod ... See more keywords
New focus on regulation of the rod photoreceptor phosphodiesterase.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2021.03.016
Abstract: Rod photoreceptor phosphodiesterase (PDE6) is the key catalytic enzyme of visual phototransduction. PDE6 is the only member of the phosphodiesterase family that consists of a heterodimeric catalytic core composed of PDE6α and PDE6β subunits and… read more here.
Keywords: pde6 pde6; rod photoreceptor; photoreceptor phosphodiesterase; pde6 ... See more keywords