Expression of exogenous PDE5 rescues photoreceptors in rd1 mice.
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DOI: 10.2174/0929867329666220216111952
Abstract: BACKGROUND Catalytic hydrolysis of cyclic guanosine monophosphate (cGMP) by phosphodiesterase 6 (PDE6) is a critical step in phototransduction signalling in photoreceptors. Mutations in the genes encoding any of the three PDE6 subunits are associated with… read more here.
Keywords: expression; rd1 mice; photoreceptors rd1; pde5 ... See more keywords