Photoredox-Promoted Selective Synthesis of C-5 Thiolated 2-Aminothiazoles from Terminal Alkynes.
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DOI: 10.1021/acs.orglett.2c03064
Abstract: A mild photoredox approach enabling the first one-step synthesis of thiolated 2-aminothiazoles has been reported. Notably, the incorporation of thio group on electron-rich heteroarenes such as aminothiazoles via conventional nucleophilic aromatic substitution (SNAr) presents a… read more here.
Keywords: selective synthesis; photoredox promoted; synthesis thiolated; promoted selective ... See more keywords