Psoralens activate and photosensitize Transient Receptor Potential channels Ankyrin type 1 (TRPA1) and Vanilloid type 1 (TRPV1)
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DOI: 10.1002/ejp.1654
Abstract: PUVA (psoralen UVA) therapy is used to treat a variety of skin conditions, such as vitiligo psoriasis, eczema and mycosis fungoides, but it is frequently accompanied by phototoxicity leading to burning pain, itch and erythema. read more here.
Keywords: photosensitize transient; receptor potential; potential channels; transient receptor ... See more keywords