A Visible‐ and NIR‐Light Responsive Photothermal Therapy Agent by Chirality‐Dependent MoO3−x Nanoparticles
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DOI: 10.1002/adfm.201906311
Abstract: Chirality‐based semiconducting nanocrystals, as an emerging area, are envisioned to have great potential in chiral sensing, biomedicine, and chiroptical devices. Herein, chiral substoichiometric molybdenum oxide (l/d‐Cys‐MoO3−x) nanoparticles are synthesized via step‐by‐step reduction treatment with chiral… read more here.
Keywords: agent; moo3 nanoparticles; photothermal therapy; chirality ... See more keywords
pH Switchable Nanoplatform for In Vivo Persistent Luminescence Imaging and Precise Photothermal Therapy of Bacterial Infection
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DOI: 10.1002/adfm.201909042
Abstract: Photothermal therapy (PTT) is one of the most promising approaches to combat multidrug‐resistant bacteria with less potential to induce resistance and systemic toxicity. However, uncontrollable distribution of photothermal agents leads to lethal temperatures for normal… read more here.
Keywords: bacterial infection; luminescence; gcs; persistent luminescence ... See more keywords
Smart Acid‐Activatable Self‐Assembly of Black Phosphorous as Photosensitizer to Overcome Poor Tumor Retention in Photothermal Therapy
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DOI: 10.1002/adfm.202003338
Abstract: Nanomaterials‐based photothermal therapy (PTT) could efficiently eliminate cancer cells in a noninvasive manner. However, nanoscale photosensitizers still suffer from several drawbacks, limiting them from being an ideal PTT approach against cancer. These include unfavorable biodistribution… read more here.
Keywords: tumor; self assembly; retention; acid activatable ... See more keywords
Near‐Infrared Light Triggered Silk Fibroin Scaffold for Photothermal Therapy and Tissue Repair of Bone Tumors
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DOI: 10.1002/adfm.202007188
Abstract: Silk fibroin (SF) has attracted great interest in bone tissue engineering due to its extraordinary characteristics in terms of mechanical properties, biocompatibility, and biodegradability. SF scaffolds are assembled by biocompatible polydopamine nanoparticles at mesoscopic scale,… read more here.
Keywords: bone; tissue; bone tumors; silk fibroin ... See more keywords
Intracellular Bottom‐up Synthesis of Ultrasmall CuS Nanodots in Cancer Cells for Simultaneous Photothermal Therapy and COX‐2 Inactivation
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DOI: 10.1002/adfm.202101297
Abstract: The clinical application of photothermal therapy (PTT) is limited by the accuracy of thermal damage and the risk of tumor metastasis and relapse induced by hyperthermia‐related inflammation. Intracellular bottom‐up synthesis (iBuS) of CuS nanoparticles from… read more here.
Keywords: cus; intracellular bottom; cus nanodots; bottom synthesis ... See more keywords
Organic Semiconducting Macromolecular Dyes for NIR‐II Photoacoustic Imaging and Photothermal Therapy
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DOI: 10.1002/adfm.202104650
Abstract: Owing to the unique advantages of photoacoustic imaging (PAI) and photothermal therapy (PTT) conducted over the near‐infrared‐II (NIR‐II) window, the development of high‐efficiency optical agents with NIR‐II light responsiveness is of great significance. Despite the… read more here.
Keywords: pai ptt; organic semiconducting; nir pai; photoacoustic imaging ... See more keywords
UCST Polymeric H2S‐Donor Fabricated Nanomedicine Managing Atherosclerosis by Gas‐Photothermal Therapy Involving a “Turning Waste into Treasure” Strategy
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DOI: 10.1002/adfm.202419295
Abstract: Atherosclerosis (AS) stands as a primary cause of vascular diseases worldwide, with its occurrence and progression being attributed to the interplay of multiple risk factors. Therefore, it is imperative to develop a comprehensive strategy aimed… read more here.
Keywords: gas photothermal; h2s donor; h2s; photothermal therapy ... See more keywords
Precise Diffusion of Gaseous H2S “Bomb” Potentiates NIR‐II Imaging‐Guided Photothermal Therapy by Relieving Heat Tolerance and Disturbing Cellular Homeostasis for Synergistic Orthotopic Glioblastoma Treatment
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DOI: 10.1002/adfm.202507384
Abstract: Although photothermal therapy (PTT) has thrived as a novel cancer treatment method with the merits of high spatiotemporal specificity and minimal invasion, the limited penetration depth and poor blood−brain barrier permeability pose significant challenges in… read more here.
Keywords: treatment; h2s; therapy; heat tolerance ... See more keywords
Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy
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DOI: 10.1002/adfm.202528658
Abstract: Engineering nanomaterial‐induced endothelial leakiness (NanoEL) through tumor vasculature gaps allows for enhanced nanotherapeutics entry into tumors. However, current NanoEL strategies require two steps and multiple particle types: first with the NanoEL agent and subsequently with… read more here.
Keywords: engineering; leakiness; tumor; gold nanoclusters ... See more keywords
Nuclear‐Targeted Multifunctional Magnetic Nanoparticles for Photothermal Therapy
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DOI: 10.1002/adhm.201601289
Abstract: The pursuit of multifunctional, innovative, more efficient, and safer cancer treatment has gained increasing interest in the research of preclinical nanoparticle-mediated photothermal therapy (PTT). Cell nucleus is recognized as the ideal target for cancer treatment… read more here.
Keywords: magnetic nanoparticles; nuclear targeted; monodisperse magnetic; cancer ... See more keywords
Self‐Confirming Magnetosomes for Tumor‐Targeted T1/T2 Dual‐Mode MRI and MRI‐Guided Photothermal Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200841
Abstract: Nanomaterials as T1/T2 dual‐mode magnetic resonance imaging (MRI) contrast agents have great potential in improving the accuracy of tumor diagnosis. Applications of such materials, however, are limited by the complicated chemical synthesis process and potential… read more here.
Keywords: guided photothermal; photothermal therapy; mri; mri guided ... See more keywords