0049 Orexin 2 receptor agonist activates pre-Bötzinger complex neurons, phrenic motoneurons and the diaphragm in rodents
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DOI: 10.1093/sleep/zsad077.0049
Abstract: Neurons in the pre-Bötzinger complex are critical for the generation of inspiratory rhythm and regulation of activity of phrenic motoneurons, which control the activity of the diaphragm. Dysregulation of this neuronal network and resulting dysfunction… read more here.
Keywords: neurons pre; tzinger complex; phrenic motoneurons; activity ... See more keywords
AMPK-Nrf2 Signaling Pathway in Phrenic Motoneurons following Cervical Spinal Cord Injury
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DOI: 10.3390/antiox11091665
Abstract: High spinal cord injuries (SCI) induce the deafferentation of phrenic motoneurons, leading to permanent diaphragm paralysis. This involves secondary injury associated with pathologic and inflammatory processes at the site of injury, and at the level… read more here.
Keywords: ampk nrf2; signaling pathway; nrf2 signaling; phrenic motoneurons ... See more keywords