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   Articles with "pht" as a keyword



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Association of Prehospital Transfusion With Mortality in Pediatric Trauma.

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recommendations! Published in 2023 at "JAMA pediatrics"

DOI: 10.1001/jamapediatrics.2023.1291

Abstract: Importance Optimal hemostatic resuscitation in pediatric trauma is not well defined. Objective To assess the association of prehospital blood transfusion (PHT) with outcomes in injured children. Design, Setting, and Participants This retrospective cohort study of… read more here.

Keywords: mortality; cohort; transfusion; pht ... See more keywords
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Calcium Phosphate-Based Nanoformulation Selectively Abolishes Phenytoin Resistance in Epileptic Neurons for Ceasing Seizures.

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recommendations! Published in 2023 at "Small"

DOI: 10.1002/smll.202300395

Abstract: Phenytoin (PHT) is a first-line antiepileptic drug in clinics, which could decrease neuronal bioelectric activity by blocking the voltage-operated sodium channels. However, the intrinsically low blood-brain-barrier (BBB)-crossing capability of PHT and upregulated expression level of… read more here.

Keywords: calcium phosphate; pht; epileptic neurons; resistance ... See more keywords
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The efficacy of inhaled nitric oxide treatment in premature infants with acute pulmonary hypertension.

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recommendations! Published in 2018 at "Early human development"

DOI: 10.1016/j.earlhumdev.2018.09.004

Abstract: BACKGROUND Although inhaled nitric oxide (iNO) therapy in term infants with pulmonary hypertension (PHT) has demonstrated definite benefit, the use of iNO in preterm infants remains inconclusive. AIMS To evaluate the impact of iNO treatment… read more here.

Keywords: pht; pulmonary hypertension; treatment premature; ino ... See more keywords
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A new method for simultaneous quantification of fosphenytoin, phenytoin and its primary metabolite 5-(4-hydroxyphenyl)-5-phenylhydantoin in whole blood by ultra-performance liquid chromatography-tandem mass spectrometry.

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recommendations! Published in 2018 at "Legal medicine"

DOI: 10.1016/j.legalmed.2018.08.006

Abstract: A method for simultaneous quantification of fosphenytoin (F-PHT), phenytoin (PHT) and its main metabolite 5-(4-hydroxyphenyl)-5-phenylhydantoin (HPPH) in whole blood was developed and validated using ultra-performance liquid chromatography-tandem mass spectrometry. Whole blood samples were pretreated by… read more here.

Keywords: chromatography; pht; mass; quantification ... See more keywords
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ELECTROCARDIOGRAM CHANGES IN PREHYPERTENSIVE SUBJECTS – EPIDEMIOLOGY OF HYPERTENSION IN CROATIA-1 (EH UH-1) STUDY

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recommendations! Published in 2022 at "Journal of Hypertension"

DOI: 10.1097/01.hjh.0000837616.97062.0b

Abstract: Objective: The aim of this study was to analyze the characteristics and changes in the ECG findings of adults with prehypertension (PHT) in a random sample of the general population included in the EH-UH 1… read more here.

Keywords: hypertension croatia; obp pht; pht uht; pht ... See more keywords
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Hypothalamic–pituitary–testicular axis derangement following chronic phenytoin–levetiracetam adjunctive treatment in male Wistar rats

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recommendations! Published in 2020 at "Andrologia"

DOI: 10.1111/and.13788

Abstract: The effects of phenytoin (PHT), levetiracetam (LEV) or their adjunctive treatment on the hypothalamic–pituitary–testicular axis in male Wistar rats were determined. Twenty‐eight male rats (150–180 g) were randomised into four groups (N = 7). Groups… read more here.

Keywords: pht; treatment; hypothalamic pituitary; pht lev ... See more keywords
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Phenytoin-induced gingival overgrowth caused by death receptor pathway malfunction.

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recommendations! Published in 2017 at "Oral diseases"

DOI: 10.1111/odi.12651

Abstract: OBJECTIVE In this study, we investigated the role of phenytoin (PHT) in death receptor-induced apoptosis of gingival fibroblasts to clarify the mechanism of PHT-induced gingival overgrowth. METHODS Human gingival fibroblasts were cultured to semiconfluence and… read more here.

Keywords: pht; death receptor; induced gingival; gingival fibroblasts ... See more keywords
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Prevalence of pulmonary hypertension in aortic regurgitation and its influence on outcomes

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recommendations! Published in 2023 at "Heart"

DOI: 10.1136/heartjnl-2022-322187

Abstract: Objective Aortic regurgitation (AR) can lead to pulmonary hypertension (PHT). There is a paucity of data on the prognostic importance of PHT in these patients. We therefore aimed to describe the prevalence and prognostic importance… read more here.

Keywords: pht; mortality; pulmonary hypertension; aortic regurgitation ... See more keywords
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Noninvasive Evaluation of Portal Hypertension Using a Supervised Learning Technique

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recommendations! Published in 2017 at "Journal of Healthcare Engineering"

DOI: 10.1155/2017/6183714

Abstract: Portal hypertension (PHT) is a key event in the evolution of different chronic liver diseases and leads to the morbidity and mortality of patients. The traditional reliable PHT evaluation method is a hepatic venous pressure… read more here.

Keywords: portal hypertension; evaluation; pht; supervised learning ... See more keywords
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Insulin potentiates the anticonvulsive activity of phenytoin against maximal electroshock-induced seizures in mice.

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recommendations! Published in 2022 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202211_30389

Abstract: INTRODUCTION The limitations imposed by the blood-brain barrier (BBB) on the sufficient accumulation of antiepileptic drugs (AEDs) in the epileptogenic focus is considered the major cause of the high percentage of morbidity and mortality cases… read more here.

Keywords: electroshock; electroshock induced; activity; pht ... See more keywords
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Main pulmonary artery-to-descending aorta ratio in computed tomography: cut-off value to diagnose pulmonary hypertension in children

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recommendations! Published in 2021 at "Polish Journal of Radiology"

DOI: 10.5114/pjr.2021.103943

Abstract: Purpose To establish a cut-off value of main pulmonary artery (MPA)/descending aorta (DA) ratio and MPA/ascending aorta (AA) ratio by computed tomography (CT) to identify pulmonary hypertension (PHT) in children. Material and methods A total… read more here.

Keywords: pht; aorta ratio; value; non pht ... See more keywords