Design, synthesis, structure-activity relationship and mechanism of action studies of a series of 4-chloro-1-phthalazinyl hydrazones as a potent agent against Leishmania braziliensis.
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DOI: 10.1016/j.ejmech.2017.01.022
Abstract: With the aim to identify a potential drug candidate to treat cutaneous leishmaniasis, a series of 1-phthalazinyl hydrazones were synthesized and tested against Leishmania braziliensis parasite, one of the main responsible of this disease in… read more here.
Keywords: leishmania braziliensis; braziliensis; phthalazinyl hydrazones; activity relationship ... See more keywords