Bioinspired Lipoproteins of Furoxans–Oxaliplatin Remodel Physical Barriers in Tumor to Potentiate T‐Cell Infiltration
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202110614
Abstract: The infiltration of cytotoxic T lymphocytes (CTLs) in tumors is critically challenged by the intricate intratumor physical barriers, which is emerging as an important issue of anticancer immunotherapy. Herein, a reduction‐sensitive nitric oxide donor conjugate… read more here.
Keywords: infiltration; cell; furoxans oxaliplatin; physical barriers ... See more keywords
Effects of spatial distance, physical barriers, and habitat on a stream fish metacommunity
Sign Up to like & getrecommendations! Published in 2020 at "Hydrobiologia"
DOI: 10.1007/s10750-020-04309-8
Abstract: Metacommunity structure depends on environmental and spatial factors. Stream fishes are constrained to disperse within dendritic networks and waterfalls and other barriers add resistance to species dispersal. We evaluated the importance of environmental and spatial… read more here.
Keywords: stream fish; metacommunity; distance; physical barriers ... See more keywords
Permeability of the city – Physical barriers of and in urban green spaces in the city of Halle, Germany
Sign Up to like & getrecommendations! Published in 2021 at "Ecological Indicators"
DOI: 10.1016/j.ecolind.2021.107555
Abstract: Abstract Urban green spaces (UGS) provide important ecosystem services in cities as they support human health and wellbeing with fresh and cool air, beauty and space for physical activities. To benefit from the positive effects,… read more here.
Keywords: physical barriers; green spaces; city halle; accessibility ... See more keywords
Mitigating COVID-19 infection disease transmission in indoor environment using physical barriers
Sign Up to like & getrecommendations! Published in 2021 at "Sustainable Cities and Society"
DOI: 10.1016/j.scs.2021.103175
Abstract: During the normalized phase of COVID-19, droplets or aerosol particles produced by infected personnel are considered as the potential source of infection with uncertain exposure risk. As such, in densely populated open spaces, it is… read more here.
Keywords: transmission; disease transmission; infection; physical barriers ... See more keywords
Drug Delivery Systems for Overcoming Physical Barriers in Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2025 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.5c00474
Abstract: The efficacy of cancer therapy largely depends on the ability of drugs to penetrate the tumor tissues. However, therapeutic outcomes are often limited by formidable physical barriers in the tumor microenvironment (TME), including the blood-brain… read more here.
Keywords: physical barriers; drug delivery; delivery systems; drug ... See more keywords
Characterizing observable COVID-19 controls in Pacific Northwest grocery stores
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Occupational and Environmental Hygiene"
DOI: 10.1080/15459624.2022.2050737
Abstract: Abstract Utilizing a longitudinal, observational study, grocery store health and safety controls implemented during the COVID-19 pandemic across stores in two cities were characterized. Sixteen stores between Seattle, WA (n = 9) and Portland, OR (n = 7) were… read more here.
Keywords: mixed effects; physical barriers; grocery stores; observable covid ... See more keywords
Three physical barriers with obvious effects on Carposina sasakii selection behavior to two dominant jujube tree volatiles
Sign Up to like & getrecommendations! Published in 2018 at "Entomologia Experimentalis et Applicata"
DOI: 10.1111/eea.12688
Abstract: The peach fruit moth (PFM), Carposina sasakii Matsumura (Lepidoptera: Carposinidae), a severe pest of Ziziphus jujuba Miller fruit trees (jujube, Rhamnaceae) mainly grown in China, has increasingly hindered the development of the jujube industry in… read more here.
Keywords: jujube tree; fruit; physical barriers; carposina sasakii ... See more keywords
Breaking down physical barriers: strategies to improve lymphocyte infiltration for effective neoantigen-based therapies
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1614228
Abstract: The cancer genomic instability drives the generation of neoantigens, making them ideal targets for immunotherapy. Neoantigen-specific tumor-infiltrating lymphocytes achieve precise tumor cell killing by recognizing neoantigens on the tumor surface, but their efficacy is limited… read more here.
Keywords: physical barriers; neoantigen; based therapies; tumor ... See more keywords
Advances in Immunotherapy for the Treatment of Adult Glioblastoma: Overcoming Chemical and Physical Barriers
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14071627
Abstract: Simple Summary The poor prognosis for glioblastoma (GBM) despite the existence of a standard-of-care treatment of resection, radiotherapy, and adjuvant chemotherapy has necessitated the exploration of other therapeutic avenues. One particularly promising avenue is an… read more here.
Keywords: physical barriers; glioblastoma; adult glioblastoma; advances immunotherapy ... See more keywords
Tackling the Problem of Tendon Adhesions: Physical Barriers Prepared from α-Amino Acid-Based Poly(ester amide)s
Sign Up to like & getrecommendations! Published in 2025 at "Polymers"
DOI: 10.3390/polym17030395
Abstract: In this work, electrospun membranes of α-amino acid based poly(ester amide)s (AAA-PEAs) from L-alanine (PEA_ala) or L-phenylalanine (PEA_phe) were successfully prepared to be used as physical barriers in the orthopedic field. Also, blends of these… read more here.
Keywords: ester amide; physical barriers; based poly; acid based ... See more keywords