Physical Frailty, Genetic Predisposition, and Incident Parkinson Disease.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2023.0183
Abstract: Importance Cross-sectional evidence implicates high prevalent frailty in patients with Parkinson disease (PD), whereas the longitudinal association remains unknown. Objectives To examine the longitudinal association of the frailty phenotype with the development of PD and… read more here.
Keywords: physical frailty; prefrailty frailty; parkinson disease; incident ... See more keywords
The interaction between physical frailty and prognostic impact of heart failure medication in elderly patients
Sign Up to like & getrecommendations! Published in 2023 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14114
Abstract: Frailty is highly prevalent and associated with poor prognoses in elderly patients with heart failure (HF). However, the potential effects of physical frailty on the benefits of HF medications in elderly patients with HF are… read more here.
Keywords: physical frailty; heart failure; elderly patients; frailty ... See more keywords
Liver frailty and all-cause mortality in the older participants of the Salus in Apulia Study.
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-021-00434-x
Abstract: The liver contribution to the biological network underlying physical frailty in aging is underestimated. How best to measure this contribution magnitude and impact on health risk trajectories in frail individuals is not yet entirely clear.… read more here.
Keywords: risk; physical frailty; mortality; frailty ... See more keywords
The “Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” (SPRINTT) randomized controlled trial: design and methods
Sign Up to like & getrecommendations! Published in 2017 at "Aging Clinical and Experimental Research"
DOI: 10.1007/s40520-016-0715-2
Abstract: The sustainability of health and social care systems is threatened by a growing population of older persons with heterogeneous needs related to multimorbidity, frailty, and increased risk of functional impairment. Since disability is difficult to… read more here.
Keywords: mobility disability; trial; disability; physical frailty ... See more keywords
Association between Healthy Eating Index-2015 and physical frailty among the United States elderly adults: the National Health and Nutrition Examination Survey (NHANES) 2011–2014
Sign Up to like & getrecommendations! Published in 2021 at "Aging Clinical and Experimental Research"
DOI: 10.1007/s40520-021-01874-3
Abstract: Diet plays an important role in the development of age-related chronic diseases. However, the association between diet quality assessed by Healthy Eating Index (HEI)-2015, the latest version of HEI, and physical frailty among the general… read more here.
Keywords: elderly adults; physical frailty; hei 2015; frailty ... See more keywords
Inflammatory signatures in older persons with physical frailty and sarcopenia: The frailty “cytokinome” at its core
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2019.04.019
Abstract: BACKGROUND The construct of physical frailty and sarcopenia (PF&S) identifies an age-related pre-disability condition defined by reduced physical performance and low muscle mass. Whether PF&S is characterized by perturbations of the cytokine network is presently… read more here.
Keywords: frailty sarcopenia; pls; gender specific; physical frailty ... See more keywords
Exploring the potential of salivary and blood immune biomarkers to elucidate physical frailty in institutionalized older women
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2019.110759
Abstract: Identification of older populations at increased risk of physical frailty using biochemical approaches could improve screening accuracy. The aim of this study was to study the relationship between immune markers and independent components of physical… read more here.
Keywords: frailty institutionalized; physical frailty; frailty; blood ... See more keywords
Vascular endothelial dysfunction may be an early predictor of physical frailty and sarcopenia: A meta-analysis of available data from observational studies
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2021.111260
Abstract: BACKGROUND Physical frailty and sarcopenia (PF & S) are major public health problems in the older population and promising predictors of adverse cardiovascular outcomes. However, the underlying mechanisms linking physical frailty, sarcopenia and adverse cardiovascular… read more here.
Keywords: frailty sarcopenia; vascular endothelial; physical frailty; frailty ... See more keywords
High Prevalence of Physical Frailty Among Community-Dwelling Malnourished Older Adults-A Systematic Review and Meta-Analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Medical Directors Association"
DOI: 10.1016/j.jamda.2016.12.074
Abstract: BACKGROUND Malnutrition and frailty are two geriatric syndromes that significantly affect independent living and health in community-dwelling older adults. Although the pathophysiology of malnutrition and physical frailty share common pathways, it is unknown to what… read more here.
Keywords: malnutrition; physical frailty; frailty; community dwelling ... See more keywords
Early-Onset Physical Frailty in Adults With Diabesity and Peripheral Neuropathy.
Sign Up to like & getrecommendations! Published in 2018 at "Canadian journal of diabetes"
DOI: 10.1016/j.jcjd.2017.12.001
Abstract: OBJECTIVES Diabesity (obesity and diabetes mellitus) has been identified as a potential contributor to early-onset frailty. Impairments contributing to early onset of physical frailty in this population are not well understood, and there is little… read more here.
Keywords: early onset; onset physical; peripheral neuropathy; physical frailty ... See more keywords
The association between brain volume, cortical brain infarcts, and physical frailty
Sign Up to like & getrecommendations! Published in 2018 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2018.06.032
Abstract: Physical frailty is an age-associated syndrome of decreased reserve leading to vulnerability to physiological stressors and associated with negative outcomes. The underlying structural brain abnormalities of physical frailty are unclear. We investigated the association between… read more here.
Keywords: volume; cortical brain; physical frailty; frailty ... See more keywords