The physical organic chemistry of glycopyranosyl transfer reactions in solution and enzyme-catalyzed.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2019.08.003
Abstract: Our understanding of the mechanisms of glycopyranosyl transfer that occur in solution, both for the chemical synthesis of complex structures and that for the cleavage of glycosidic bonds has allowed us to design biologically active… read more here.
Keywords: glycopyranosyl transfer; chemistry; physical organic; transfer ... See more keywords
Using Physical Organic Chemistry Knowledge to Predict Unusual Metabolites of Synthetic Phenolic Antioxidants by Cytochrome P450.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.2c00021
Abstract: Biotransformation, especially by human CYP450 enzymes, plays a crucial role in regulating the toxicity of organic compounds in organisms, but is poorly understood for most emerging pollutants, as their numerous "unusual" biotransformation reactions cannot retrieve… read more here.
Keywords: organic chemistry; phenolic antioxidants; synthetic phenolic; unusual metabolites ... See more keywords
Delineating Physical Organic Parameters in Site-Selective C–H Functionalization of Indoles
Sign Up to like & getrecommendations! Published in 2018 at "ACS Central Science"
DOI: 10.1021/acscentsci.8b00264
Abstract: Site-selective C–H functionalization is a great challenge in homogeneous transition-metal catalysis. Herein, we present a physical organic approach to delineate the origin of regioselective amidation of N-acylindoles through Ir(III) catalysis. Bulkiness of N-directing groups of… read more here.
Keywords: selective functionalization; site selective; physical organic; delineating physical ... See more keywords
Physical Organic Approach to Persistent, Cyclable, Low-Potential Electrolytes for Flow Battery Applications.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b00147
Abstract: The deployment of nonaqueous redox flow batteries for grid-scale energy storage has been impeded by a lack of electrolytes that undergo redox events at as low (anolyte) or high (catholyte) potentials as possible while exhibiting… read more here.
Keywords: approach persistent; low potential; organic approach; physical organic ... See more keywords