Flucytosine‐based prodrug activation by cold physical plasma
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200061
Abstract: Reactive oxygen species (ROS) are known to trigger drug release from arylboronate‐containing ROS‐responsive prodrugs. In cancer cells, elevated levels of ROS can be exploited for the selective activation of prodrugs via Baeyer–Villiger type oxidation rearrangement… read more here.
Keywords: physical plasma; cold physical; flucytosine based; prodrug activation ... See more keywords
Role of Ambient Gas Composition on Cold Physical Plasma-Elicited Cell Signaling in Keratinocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.04.030
Abstract: A particularly promising medical application of cold physical plasma is the support of wound healing. This is presumably achieved by modulating inflammation as well as skin cell signaling and migration. Plasma-derived reactive oxygen and nitrogen… read more here.
Keywords: plasma; physical plasma; cell signaling; role ... See more keywords
Immunogenic Cell Death In Murine Colon-Carcinoma Cells Following Exposure To Cold Physical Plasma-Treated Saline Solution
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Plasma Medicine"
DOI: 10.1016/j.cpme.2017.12.030
Abstract: Diffuse peritoneal metastasis of gastrointestinal tumors is a life-threatening complication in end-stage tumor patients. Standard of care is hyperthermic intraperitoneal chemotherapy (HIPEC) and/or radiation therapy, both associated with significant side effects [1]. Previous studies have… read more here.
Keywords: plasma; plasma treated; physical plasma; cold physical ... See more keywords
Combining cold physical plasma with pulsed electrical fields for cancer treatment
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Plasma Medicine"
DOI: 10.1016/j.cpme.2017.12.042
Abstract: Pallation of end-stage melanoma and breast cancer patients is a challenge. Despite the generally successful use of electrochemotherapy (ECT) in these patients, response rates can still be improved. Previous studies demonstrated the anticancer potential of… read more here.
Keywords: physical plasma; treatment; cold physical; cancer treatment ... See more keywords
xCT (SLC7A11) expression confers intrinsic resistance to physical plasma treatment in tumor cells
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2019.101423
Abstract: Cold physical plasma is a partially ionized gas investigated as a new anticancer tool in selectively targeting cancer cells in monotherapy or in combination with therapeutic agents. Here, we investigated the intrinsic resistance mechanisms of… read more here.
Keywords: plasma; physical plasma; cell lines; tumor cells ... See more keywords
Cold Physical Plasma Toxicity in Breast and Oral Squamous Carcinoma In Vitro and in Patient-Derived Cancer Tissue Ex Vivo
Sign Up to like & getrecommendations! Published in 2023 at "Applied Sciences"
DOI: 10.3390/app13116472
Abstract: Breast cancer (BC) and oral squamous cell carcinoma (OSCC) are among the most common types of cancer, but current clinical outcomes remain unsatisfactory. Available therapies have limitations in terms of efficacy and may also cause… read more here.
Keywords: physical plasma; vivo; cold physical; plasma ... See more keywords
Impact of Non-Invasive Physical Plasma on Heat Shock Protein Functionality in Eukaryotic Cells
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11051471
Abstract: Recently, biomedical research has increasingly investigated physical plasma as an innovative therapeutic approach with a number of therapeutic biomedical effects. It is known from radiation and chemotherapy that these applications can lead to the induction… read more here.
Keywords: impact non; plasma; physical plasma; heat shock ... See more keywords
Impact of ROS Generated by Chemical, Physical, and Plasma Techniques on Cancer Attenuation
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11071030
Abstract: For the last few decades, while significant improvements have been achieved in cancer therapy, this family of diseases is still considered one of the deadliest threats to human health. Thus, there is an urgent need… read more here.
Keywords: generated chemical; physical plasma; chemical physical; ros generated ... See more keywords
Noninvasive Physical Plasma as Innovative and Tissue-Preserving Therapy for Women Positive for Cervical Intraepithelial Neoplasia
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14081933
Abstract: Simple Summary The treatment of cervical intraepithelial neoplasia (CIN) is still associated with the use of invasive therapeutic procedures. Although CIN 1/2 lesions show high remission rates, treatment is necessary in individual cases and noninvasive… read more here.
Keywords: treatment; noninvasive physical; cervical intraepithelial; intraepithelial neoplasia ... See more keywords
Enhancing the Impact of Chemotherapy on Ewing Sarcoma Cells through Combination with Cold Physical Plasma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108669
Abstract: Although Ewing’s sarcoma (ES) is a rare, but very aggressive tumor disease affecting the musculoskeletal system, especially in children, it is very aggressive and difficult to treat. Although medical advances and the establishment of chemotherapy… read more here.
Keywords: physical plasma; cold physical; ewing sarcoma; combination ... See more keywords