Abstract 614: CD137 (4-1BB) requires physically associated cIAPs for signal transduction and antitumor effects
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DOI: 10.1158/1538-7445.am2023-614
Abstract: CD137 (4-1BB) is a member of the TNFR family, whose expression is induced on antigen-primed T cells and that mediates potent costimulatory signals upon ligation by CD137L or agonist monoclonal antibodies. CD137 agonists attain immunotherapeutic… read more here.
Keywords: cd137 1bb; cd137; physically associated; antitumor effects ... See more keywords