Sulfoximines from a Medicinal Chemist's Perspective: Physicochemical and in vitro Parameters Relevant for Drug Discovery.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2016.09.091
Abstract: Sulfoximines, sulfondiimides and sulfonimidamides are fascinating but not yet fully explored variants of the common sulfone or sulfonamide motif. In this study, we report the physicochemical and in vitro properties of sulfoximines and compare them with… read more here.
Keywords: drug discovery; sulfoximines medicinal; physicochemical vitro;
Physicochemical and in-vitro biological analysis of bio-functionalized titanium samples in a protein-rich medium.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2019.03.019
Abstract: The long-term survivability of the implants is strongly influenced by the osseointegration aspects of the metal-bone interface. In this study, biological materials such as fibrinogen and fibrin are used to functionalize titanium surfaces to enhance… read more here.
Keywords: biofunctionalized samples; titanium; osseointegration; bio functionalized ... See more keywords
Physicochemical and in vitro biological evaluations of furazolidone-based β-cyclodextrin complexes in Leishmania amazonensis.
Sign Up to like & getrecommendations! Published in 2018 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2018.06.013
Abstract: Recently, there have been numerous cases of leishmaniasis reported in different Brazilian states. The use of furazolidone (FZD) to treat leishmaniasis has been previously described; however, the drug is associated with adverse effects such as… read more here.
Keywords: amazonensis; furazolidone based; vitro biological; evaluations furazolidone ... See more keywords
Physicochemical and In Vitro Evaluation of Drug Delivery of an Antibacterial Synthetic Benzophenone in Biodegradable PLGA Nanoparticles
Sign Up to like & getrecommendations! Published in 2018 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-018-1187-9
Abstract: Due to the increasing incidents of antimicrobial-resistant pathogens, the development of new antibiotics and their efficient formulation for suitable administration is crucial. Currently, one group of promising antimicrobial compounds are the benzophenone tetra-amides which show… read more here.
Keywords: plga nanoparticles; vitro evaluation; drug; benzophenone ... See more keywords
Physicochemical and In Vitro Starch Residual Digestion Structures of Extruded Maize and Sorghum Starches Added with Sodium Stearoyl Lactylate
Sign Up to like & getrecommendations! Published in 2023 at "Foods"
DOI: 10.3390/foods12101988
Abstract: This research aimed to characterize the physicochemical, in vitro digestion, and structural features of digestion residues of maize and sorghum starches subjected to thermoplastic extrusion, along with the influence of Sodium Stearoyl Lactylate (SSL), to… read more here.
Keywords: physicochemical vitro; starch; sorghum starches; maize sorghum ... See more keywords
Regiospecific Positioning of Palmitic Acid in Triacylglycerol Structure of Enzymatically Modified Lipids Affects Physicochemical and In Vitro Digestion Properties
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26134015
Abstract: Tripalmitin-(PPP, 81.2%), 1,3-dipalmitoyl-2-oleoylglycerol-(POP, 64.4%), 1,2-dipalmitoyl-3-oleoylglycerol-(PPO, 86.5%), and 1,3-dioleoyl-2-palmitoylglycerol-(OPO, 50.2%)-rich lipids with different regiospecific positions of palmitic acid (P) were synthesized via acetone fractionation and lipase-catalyzed acidolysis, and their physicochemical and hydrolytic characteristics were compared. Triacylglycerols… read more here.
Keywords: palmitic acid; vitro digestion; opo rich; digestion ... See more keywords