Mouse models of sporadic thyroid cancer derived from BRAFV600E alone or in combination with PTEN haploinsufficiency under physiologic TSH levels
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DOI: 10.1371/journal.pone.0201365
Abstract: The BRAFV600E mutation is the most prevalent driver mutation of sporadic papillary thyroid cancers (PTC). It was previously shown that prenatal or postnatal expression of BRAFV600E under elevated TSH levels induced thyroid cancers in several… read more here.
Keywords: mouse models; physiologic tsh; expression; brafv600e ... See more keywords