In Vitro Studies on Physiological and Chemical Stability of New LE404-Derivatives with Extended Half-Life.
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DOI: 10.1055/s-0044-102096
Abstract: Dibenzoazecines are a class of potential neuroleptics with high affinity to dopamine and serotonin receptors. The efficacy and high therapeutic range has already been demonstrated in vivo with the lead structure 7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecin-3-ol (LE404: ) and… read more here.
Keywords: physiological chemical; chemical stability; studies physiological; stability ... See more keywords