Analysis of the GPR17 receptor in NG2‐glia under physiological conditions unravels a new subset of oligodendrocyte progenitor cells with distinct functions
Sign Up to like & getrecommendations! Published in 2023 at "Glia"
DOI: 10.1002/glia.24356
Abstract: NG2‐glia comprise a heterogeneous population of cycling cells that give rise to mature, myelinating oligodendrocytes. The mechanisms that regulate the process of differentiation from NG2‐glia into oligodendrocytes are still not fully understood but over the… read more here.
Keywords: gpr17; physiological conditions; gpr17 receptor; ng2 glia ... See more keywords
Clinical Implications of UCP1 mRNA Expression in Human Cervical Adipose Tissue Under Physiological Conditions
Sign Up to like & getrecommendations! Published in 2018 at "Obesity"
DOI: 10.1002/oby.22188
Abstract: The clinical implications of human brown adipose tissue (BAT) were investigated based on the analysis of cervical adipose tissue gene expression under normal physiological conditions. read more here.
Keywords: cervical adipose; clinical implications; tissue; expression ... See more keywords
Yeast Nucleoplasmic Extracts and an Application to Visualize Chromatin Assembly on Single Molecules of DNA.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0868-5_15
Abstract: In eukaryotic cells, the genomic DNA is packaged into chromatin, the basic unit of which is the nucleosome. Studying the mechanism of chromatin formation under physiological conditions is inherently difficult due to the limitations of… read more here.
Keywords: chromatin assembly; extracts application; chromatin; nucleoplasmic extracts ... See more keywords
Tribological properties of microporous polydimethylsiloxane (PDMS) surfaces under physiological conditions.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2019.11.082
Abstract: Textured biomaterials have been extensively used in biomedical engineering to modulate mammalian and bacterial cell adhesion and proliferation, implant integration with human body and infection prevention. However, the tribological implications of texturing under wet physiological… read more here.
Keywords: tribological properties; polydimethylsiloxane pdms; pdms; physiological conditions ... See more keywords
Reactions of ferric hemoglobin and myoglobin with hydrogen sulfide under physiological conditions.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2018.02.007
Abstract: Ferric hemoglobin (metHb) and myoglobin (metMb), present at low levels in vivo, have been recently found to oxidize hydrogen sulfide (H2S) in excess, thus potentially contributing to removal of toxic H2S in blood and heart,… read more here.
Keywords: methb; hydrogen sulfide; ferric hemoglobin; myoglobin ... See more keywords
Metalloglycosidase Mimics: Oxidative Cleavage of Saccharides Promoted by Multinuclear Copper Complexes under Physiological Conditions.
Sign Up to like & getrecommendations! Published in 2020 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.0c01193
Abstract: Degradation of saccharides is relevant to the design of catalytic therapeutics, the production of biofuels, inhibition of biofilms, as well as other applications in chemical biology. Herein, we report the design of multinuclear Cu complexes… read more here.
Keywords: cleavage; cleavage saccharides; chemistry; copper ... See more keywords
Melanoidins from Coffee, Cocoa, and Bread Are Able to Scavenge α-Dicarbonyl Compounds under Simulated Physiological Conditions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Agricultural and Food Chemistry"
DOI: 10.1021/acs.jafc.9b03744
Abstract: Free amino residues react with α-dicarbonyl compounds (DCs) contributing to the formation of advanced glycation end products (AGEs). Phenolic compounds can scavenge DCs, thus controlling the dietary carbonyl load. This study showed that high-molecular weight… read more here.
Keywords: simulated physiological; dicarbonyl compounds; bread; cocoa ... See more keywords
Lipopolysaccharide enters the rat brain by a lipoprotein-mediated transport mechanism in physiological conditions
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-13302-6
Abstract: Physiologically, lipopolysaccharide (LPS) is present in the bloodstream and can be bound to several proteins for its transport (i.e.) LPS binding protein (LBP) and plasma lipoproteins). LPS receptors CD14 and TLR-4 are constitutively expressed in… read more here.
Keywords: transport mechanism; physiological conditions; brain; lipoprotein ... See more keywords
The ELISA Detectability and Potency of Pegfilgrastim Decrease in Physiological Conditions: Key Roles for Aggregation and Individual Variability
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-59346-z
Abstract: PEGylated recombinant human granulocyte colony stimulating factor (pegfilgrastim) is used clinically to accelerate immune reconstitution following chemotherapy and is being pursued for biosimilar development. One challenge to overcome in pegfilgrastim biosimilar development is establishing pharmacokinetic… read more here.
Keywords: individual variability; variability elisa; variability; pegfilgrastim ... See more keywords
Stabilizing gelatin-based bioinks under physiological conditions by incorporation of ethylene-glycol-conjugated Fmoc-FF peptides.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d1nr08206j
Abstract: Over the last decade, three-dimensional (3D) printing technologies have attracted the interest of researchers due to the possibility of fabricating tissue- and organ-like structures with similarities to the organ of interest. One of the most… read more here.
Keywords: based bioinks; stabilizing gelatin; gelatin based; fmoc ... See more keywords
Self-assembly of an MRI responsive agent under physiological conditions provides an extended time window for in vivo imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03126d
Abstract: An MRI-responsive agent that spontaneously self-assembles to a large supramolecular structure under physiological conditions was designed. The obtained assembly provides an extended time window for in vivo studies, as demonstrated for a fluorine-19 probe constructed… read more here.
Keywords: responsive agent; mri responsive; time window; provides extended ... See more keywords