Metabolic effects of physiological levels of caffeine in myotubes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Physiology and Biochemistry"
DOI: 10.1007/s13105-017-0601-1
Abstract: Caffeine has been shown to stimulate multiple major regulators of cell energetics including AMP-activated protein kinase (AMPK) and Ca2+/calmodulin-dependent protein kinase II (CaMKII). Additionally, caffeine induces peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) and mitochondrial… read more here.
Keywords: physiological levels; metabolism; caffeine; oxidative metabolism ... See more keywords
Physiological levels of 25-hydroxyvitamin D3 induce a suppressive CD4+ T cell phenotype not reflected in the epigenetic landscape.
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian journal of immunology"
DOI: 10.1111/sji.13146
Abstract: 1,25-dihydroxyvitamin D3 (1,25(OH)2 D3 ), the active metabolite of vitamin D3 has a strong impact on the differentiation and function of immune cells. Here we analyzed the influence of its precursor 25-hydroxyvitamin D3 (25(OH)D3 )… read more here.
Keywords: cd4; physiological levels; hydroxyvitamin induce; levels hydroxyvitamin ... See more keywords
Up-regulated chitinase-like protein-1 promotes tumour growth while physiological levels are protective
Sign Up to like & getrecommendations! Published in 2025 at "Life Science Alliance"
DOI: 10.26508/lsa.202403138
Abstract: CHI3L1/Chil1 is a pro-inflammatory protein that at physiological levels is tissue-protective, whereas up-regulated expression is tumorigenic, rendering it a valid but context-sensitive therapeutic target. The human and mouse orthologues CHI3L1/Chil1 encode a chitinase-related protein that… read more here.
Keywords: physiological levels; inflammatory; protein; chitinase ... See more keywords