Multifunctional biomedical imaging in physiological and pathological conditions using a NIR-II probe.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced functional materials"
DOI: 10.1002/adfm.201700995
Abstract: Compared with imaging in the visible (400 - 650 nm) and near-infrared window I (NIR-I, 650 - 900 nm) regions, imaging in near-infrared window II (NIR-II, 1,000-1,700 nm) is a highly promising in vivo imaging… read more here.
Keywords: multifunctional biomedical; probe; physiological pathological; pathological conditions ... See more keywords
Gut Microbiota and IL-17A: Physiological and Pathological Responses
Sign Up to like & getrecommendations! Published in 2017 at "Probiotics and Antimicrobial Proteins"
DOI: 10.1007/s12602-017-9329-z
Abstract: IL-17A is a cytokine which is produced by several immune and non-immune cells. The cytokine plays dual roles from protection from microbes and protection from pro-inflammatory based diseases to induction of the pro-inflammatory based diseases.… read more here.
Keywords: 17a physiological; physiological pathological; microbiota 17a; pathological responses ... See more keywords
Emerging physiological and pathological roles of MeCP2 in non-neurological systems.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.108768
Abstract: Numerous neurological and non-neurological disorders are associated with dysfunction of epigenetic modulators, and methyl CpG binding protein 2 (MeCP2) is one of such proteins. Initially identified as a transcriptional repressor, MeCP2 specifically binds to methylated… read more here.
Keywords: emerging physiological; non neurological; physiological pathological; pathological roles ... See more keywords
Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2020.104833
Abstract: Abstract The renin-angiotensin system (RAS) is crucial for the physiology and pathology of all the organs. Angiotensin-converting enzyme 2 (ACE2) maintains the homeostasis of RAS as a negative regulator. Recently, ACE2 was identified as the… read more here.
Keywords: regulation ace2; physiological pathological; ace2; receptor ... See more keywords
Physiological, Pathological, and Targetable Membraneless Organelles in Neurons
Sign Up to like & getrecommendations! Published in 2019 at "Trends in Neurosciences"
DOI: 10.1016/j.tins.2019.08.005
Abstract: Neurons require unique subcellular compartmentalization to function efficiently. Formed from proteins and RNAs through liquid-liquid phase separation, membraneless organelles (MLOs) have emerged as one way in which cells form distinct, specialized compartments in the absence… read more here.
Keywords: membraneless organelles; physiological pathological; targetable membraneless; membraneless ... See more keywords
Mechanisms of physiological and pathological cardiac hypertrophy
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-018-0007-y
Abstract: Cardiomyocytes exit the cell cycle and become terminally differentiated soon after birth. Therefore, in the adult heart, instead of an increase in cardiomyocyte number, individual cardiomyocytes increase in size, and the heart develops hypertrophy to… read more here.
Keywords: cardiac hypertrophy; mechanisms physiological; heart; physiological pathological ... See more keywords
Interleukin-27 controls basal pain threshold in physiological and pathological conditions
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-29398-3
Abstract: Numerous studies have shown that pain sensation is affected by various immune molecules, such as cytokines, in tissues comprising the sensory pathway. Specifically, it has been shown that interleukin (IL)-17 promotes pain behaviour, but IL-10… read more here.
Keywords: physiological pathological; pathological conditions; pain sensation; chronic pain ... See more keywords
Transcriptional profiling in microglia across physiological and pathological states identifies a transcriptional module associated with neurodegeneration
Sign Up to like & getrecommendations! Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-024-06684-7
Abstract: Microglia are the resident immune cells of the central nervous system and are involved in brain development, homeostasis, and disease. New imaging and genomics technologies are revealing microglial complexity across developmental and functional states, brain… read more here.
Keywords: disease; microglia across; across physiological; physiological pathological ... See more keywords
TLR2 and TLR4 bridge physiological and pathological inflammation in the reproductive system
Sign Up to like & getrecommendations! Published in 2025 at "Communications Biology"
DOI: 10.1038/s42003-025-08424-x
Abstract: Toll-like receptors (TLRs), particularly TLR2 and TLR4, are critical components of the innate immune system that play significant roles in reproductive biology beyond their well-established functions in immune defense. These receptors recognize distinct pathogen-associated molecular… read more here.
Keywords: physiological pathological; biology; pathological inflammation; tlr2 tlr4 ... See more keywords
Physiological and pathological roles of locally expressed kisspeptin and KISS1R in the endometrium.
Sign Up to like & getrecommendations! Published in 2023 at "Human reproduction"
DOI: 10.1093/humrep/dead080
Abstract: Kisspeptins, encoded by the KISS1 gene, are a family of polypeptides that bind the kisspeptin receptor (KISS1R) to perform biological functions. Produced mainly in the hypothalamus, these neuropeptides regulate the pulsatile secretion of GnRH and… read more here.
Keywords: physiological pathological; kisspeptin kiss1r; kiss1r; kiss1r endometrium ... See more keywords
Nogo-B modulates physiological and pathological angiogenesis during development and disease
Sign Up to like & getrecommendations! Published in 2024 at "Physiology"
DOI: 10.1152/physiol.2024.39.s1.1641
Abstract: Angiogenesis, i.e., the formation of new blood vessels, is essential for normal development and functional vessel formation in ischemic diseases. During angiogenesis, endothelial cells (ECs) coordinate migration, proliferation, and metabolic fluxes to adapt to branching… read more here.
Keywords: loss nogo; physiology; pathological angiogenesis; physiological pathological ... See more keywords