Articles with "physiologically downregulated" as a keyword



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SMN Is Physiologically Downregulated at Wild-Type Motor Nerve Terminals but Aggregates Together with Neurofilaments in SMA Mouse Models

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Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12101524

Abstract: Survival motor neuron (SMN) is an essential and ubiquitously expressed protein that participates in several aspects of RNA metabolism. SMN deficiency causes a devastating motor neuron disease called spinal muscular atrophy (SMA). SMN forms the… read more here.

Keywords: nerve terminals; microscopy; physiologically downregulated; motor ... See more keywords