Mechanical Response of Neural Cells to Physiologically Relevant Stiffness Gradients
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201901036
Abstract: Abstract Understanding the influence of the mechanical environment on neurite behavior is crucial in the development of peripheral nerve repair solutions, and could help tissue engineers to direct and guide regeneration. In this study, a… read more here.
Keywords: response neural; stiffness; mechanical response; physiologically relevant ... See more keywords
Light-based 3D printing of gelatin-based biomaterial inks to Create a Physiologically Relevant in Vitro Fish Intestinal Model.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202300016
Abstract: To provide prominent accessibility of fishmeal to the European population, the currently available, time- and cost-extensive feeding trials, which evaluate fish feed, should be replaced. The current paper reports on the development of a novel… read more here.
Keywords: light based; based biomaterial; printing gelatin; physiologically relevant ... See more keywords
Polyhistidine-Based Metal Coordination Hydrogels with Physiologically Relevant pH Responsiveness and Enhanced Stability through a Novel Synthesis.
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecular rapid communications"
DOI: 10.1002/marc.201800109
Abstract: Utilizing the abnormal physiological conditions of disease tissues can result in a site-specific functionality with high control and efficiency of stimuli-responsive hydrogels. Here, a physiologically relevant pH-responsive and self-healing hydrogel is reported based on coordination… read more here.
Keywords: polyhistidine based; coordination; based metal; hydrogels physiologically ... See more keywords
A physiologically relevant, estradiol‐17β [E2]‐responsive in vitro tissue‐engineered model of the vaginal epithelium for vaginal tissue research
Sign Up to like & getrecommendations! Published in 2022 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.24908
Abstract: There are many situations where preclinical models of the human vagina would be valuable for in vitro studies into the pathophysiology of vaginally transmitted diseases, microbicide efficacy, irritability testing, and particularly, for assessing materials to… read more here.
Keywords: relevant estradiol; model; physiologically relevant; vaginal tissue ... See more keywords
Micropattern-based platform as a physiologically relevant model to study epithelial morphogenesis and nephrotoxicity.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119339
Abstract: Tubulogenesis in epithelial organs often initiates with the acquisition of apicobasal polarity, giving rise to the formation of small lumens that expand and fuse to generate a single opened cavity. In this study, we present… read more here.
Keywords: study; micropattern based; morphogenesis; platform ... See more keywords
How Can Microfluidic and Microfabrication Approaches Make Experiments More Physiologically Relevant?
Sign Up to like & getrecommendations! Published in 2020 at "Cell systems"
DOI: 10.1016/j.cels.2020.07.003
Abstract: Microfabricated and microfluidic devices enable standardized handling, precise spatiotemporal manipulation of cells and liquids, and recapitulation of cellular environments, tissues, and organ-level biology. We asked researchers how these devices can make in vitro experiments more physiologically… read more here.
Keywords: microfabrication approaches; microfluidic microfabrication; make experiments; experiments physiologically ... See more keywords
A novel assay provides sensitive measurement of physiologically relevant changes in albumin permeability in isolated human and rodent glomeruli
Sign Up to like & getrecommendations! Published in 2018 at "Kidney International"
DOI: 10.1016/j.kint.2017.12.003
Abstract: Increased urinary albumin excretion is a key feature of glomerular disease but has limitations as a measure of glomerular permeability. Here we describe a novel assay to measure the apparent albumin permeability of single capillaries… read more here.
Keywords: novel assay; albumin permeability; rodent glomeruli; permeability ... See more keywords
Biological Thiols and Carbon Disulfide: The Formation and Decay of Trithiocarbonates under Physiologically Relevant Conditions
Sign Up to like & getrecommendations! Published in 2017 at "ACS Omega"
DOI: 10.1021/acsomega.7b01206
Abstract: Carbon disulfide is an environmental toxin, but there are suggestions in the literature that it may also have regulatory and/or therapeutic roles in mammalian physiology. Thiols or thiolates would be likely biological targets for an… read more here.
Keywords: carbon disulfide; decay; physiologically relevant; formation ... See more keywords
A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-33759-3
Abstract: Cartilage provides low-friction properties and plays an essential role in diarthrodial joints. A hydrated ground substance composed mainly of proteoglycans (PGs) and a fibrillar collagen network are the main constituents of cartilage. Unfortunately, traumatic joint… read more here.
Keywords: model; novel mechanobiological; physiologically relevant; relevant dynamic ... See more keywords
Physiologically relevant pH- and temperature-responsive polypeptide hydrogels with adhesive properties
Sign Up to like & getrecommendations! Published in 2021 at "Polymer Chemistry"
DOI: 10.1039/d1py00290b
Abstract: Physiologically relevant pH- and temperature-responsive polypeptide hydrogels with adhesive properties were developed and characterized. read more here.
Keywords: hydrogels adhesive; relevant temperature; polypeptide hydrogels; responsive polypeptide ... See more keywords
67 Development of a Physiologically-Relevant in Vitro Model of the Lung, Incorporating Novel Peptide Hydrogels as Biomimetic Extracellular Matrix Scaffolds
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Work Exposures and Health"
DOI: 10.1093/annweh/wxac087.199
Abstract: The vast number of different nanomaterials (NMs) in production and under development precludes the complete hazard assessment of each individual substance according to current regulatory standards which require long term in vivo studies. To reduce… read more here.
Keywords: toxicology; extracellular matrix; development; model ... See more keywords