Efficacy of antidotes and their combinations in the treatment of acute carbamate poisoning in rats.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology"
DOI: 10.1016/j.tox.2018.08.017
Abstract: BACKGROUND Physostigmine and its analogues neostigmine, pyridostigmine and rivastigmine are carbamates nowadays used in many indications, including antidotal effects against antimuscarinic poisonings, reversal of competitive neuromuscular block, myasthenia gravis, Alzheimer's disease and prophylaxis against nerve… read more here.
Keywords: protection; ache; hexamethonium; pyridostigmine ... See more keywords
Physostigmine for prevention of postoperative delirium and long-term cognitive dysfunction in liver surgery
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Anaesthesiology"
DOI: 10.1097/eja.0000000000001456
Abstract: Supplemental Digital Content is available in the text BACKGROUND Anecdotally, cholinergic stimulation has been used to treat delirium and reduce cognitive dysfunction. OBJECTIVE The aim of this investigation was to evaluate whether physostigmine reduced the… read more here.
Keywords: physostigmine; placebo; surgery; cognitive dysfunction ... See more keywords