Anti-melanogenic activity of phytosphingosine via the modulation of the microphthalmia-associated transcription factor signaling pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2017.03.011
Abstract: BACKGROUND Microphthalmia-associated transcription factor (MITF) suppresses the expression of enzymes controlling the production of melanin. Phytosphingosine is a well-known cosmetic agent, but its anti-melanogenic activity and mechanism of action remain unclear. OBJECTIVE This study was… read more here.
Keywords: transcription; mitf; phytosphingosine; melanogenic activity ... See more keywords
A decrease in Flavonifractor plautii and its product, phytosphingosine, predisposes individuals with phlegm-dampness constitution to metabolic disorders
Sign Up to like & getrecommendations! Published in 2025 at "Cell Discovery"
DOI: 10.1038/s41421-025-00789-x
Abstract: According to traditional Chinese medicine (TCM) constitutional theory, individuals with phlegm-dampness constitution (PDC) are at increased risk for metabolic disorders. Previous studies have indicated that PDC individuals exhibit gene expression changes associated with metabolic disorders,… read more here.
Keywords: phlegm dampness; dampness constitution; individuals phlegm; metabolic disorders ... See more keywords
The major plant sphingolipid long chain base phytosphingosine inhibits growth of bacterial and fungal plant pathogens
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-05083-4
Abstract: Sphingolipid long chain bases (LCBs) are building blocks of sphingolipids and can serve as signalling molecules, but also have antimicrobial activity and were effective in reducing growth of a range of human pathogens. In plants,… read more here.
Keywords: phytosphingosine; long chain; growth; major plant ... See more keywords