Effect of Pomegranate Extract in Mesenchymal Stem Cells by Modulation of MicroRNA-155, MicroRNA-21, MicroRNA-23b, MicroRNA-126a, and PI3K\AKT1\NF-[Formula: see text]B Expression.
Sign Up to like & getrecommendations! Published in 2020 at "DNA and cell biology"
DOI: 10.1089/dna.2020.5775
Abstract: Today, mesenchymal stem cells (MSCs) are candidates for various autoimmune disease treatments due to immunomodulatory activity in these cells. Much research has recently been done to improve the immunomodulatory activity of MSCs. Genetic variation is… read more here.
Keywords: pi3k akt1; formula see; akt1 formula; mscs ... See more keywords
Nicorandil mitigates amiodarone‐induced pulmonary toxicity and fibrosis in association with the inhibition of lung TGF‐β1/PI3K/Akt1‐p/mTOR axis in rats
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13728
Abstract: The long‐term side effect of the antiarrhythmic drug, amiodarone (AMIO), such as lung toxicity, remains a critical clinical issue. The previous knowledge denotes diverse antioxidant, anti‐inflammatory, and antifibrotic properties of the anti‐anginal drug, nicorandil (NI).… read more here.
Keywords: pi3k akt1; mtor axis; amio; toxicity ... See more keywords
Puerarin attenuates locomotor and cognitive deficits as well as hippocampal neuronal injury through the PI3K/Akt1/GSK-3β signaling pathway in an in vivo model of cerebral ischemia
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DOI: 10.18632/oncotarget.22290
Abstract: Ischemic stroke causes irreversible damage to the brain. The hippocampus is a vulnerable region and plays an important role in cognition and locomotor activity. Puerarin is a phytoestrogen that has beneficial effects in treating neurological… read more here.
Keywords: puerarin; pi3k akt1; signaling pathway; ischemia ... See more keywords
Gou Qi Zi inhibits proliferation and induces apoptosis through the PI3K/AKT1 signaling pathway in non-small cell lung cancer
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DOI: 10.3389/fonc.2022.1034750
Abstract: Background Gou Qi Zi (Lycium barbarum) is a traditional herbal medicine with antioxidative effects. Although Gou Qi Zi has been used to prevent premature aging and in the treatment of non-small cell lung cancer (NSCLC),… read more here.
Keywords: pi3k akt1; signaling pathway; akt1 signaling; gou ... See more keywords