PI3K in cancer: its structure, activation modes and role in shaping tumor microenvironment.
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DOI: 10.2217/fon-2017-0588
Abstract: The role of PI3K in cancer has been well established, and mutations of PIK3CA, the gene coding for catalytic subunit p110α of PI3K, are found in approximately 30% human cancers. The hyperactivated PI3K pathway plays… read more here.
Keywords: pi3k; pi3k cancer; activation modes; role ... See more keywords