O37 Salidroside prevents toxicity induced by delayed treatment of tPA in a rat model of focal cerebral ischemia involving PKA-and PI3K-dependent Akt activation
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2017.06.102
Abstract: Ischemic stroke is currently treated with thrombolytic therapy with the drawback that it induces hemorrhagic transformation (HT) if applied beyond its relatively narrow treatment time window. The present study was designed to examine the role… read more here.
Keywords: treatment; delayed treatment; toxicity; pi3k dependent ... See more keywords
Abstract 1116: The role of ADAM9 and PI3K-dependent NF-kappa B pathway in promoting metastasis of triple-negative breast cancer
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-1116
Abstract: Objectives: As a zinc-dependent proteinase family member, A Disintegrin and Metalloproteinase 9 (ADAM9) has the metalloproteinase domain that performs proteolytic function to liberate or shed factors, such as bFGF, VEGF, EGF, TGF-α and IGF, from… read more here.
Keywords: pi3k dependent; cancer; breast cancer; cell ... See more keywords