Enhanced antitumor immunity through sequential targeting of PI3Kδ and LAG3
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DOI: 10.1136/jitc-2020-000693
Abstract: Background Despite striking successes, immunotherapies aimed at increasing cancer-specific T cell responses are unsuccessful in most patients with cancer. Inactivating regulatory T cells (Treg) by inhibiting the PI3Kδ signaling enzyme has shown promise in preclinical… read more here.
Keywords: pi3k; pi3k lag3; lag3; regressor ... See more keywords