Abstract P4-08-06: Phosphorylation of insulin-like growth factor-1 receptor (IGF-1R) is associated with tamoxifen resistance by activating the PI3K/MAPK pathway
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs17-p4-08-06
Abstract: Background IGF-1R is overexpressed in a substantial number of breast cancer cases. When phosphorylated, IGF-1R activates the PI3K and MAPK pathways. In preclinical studies, IGF-1R overexpression has been described to be associated with tamoxifen resistance.… read more here.
Keywords: pi3k mapk; mapk pathway; igf; tamoxifen ... See more keywords
An overview of the myocardial regeneration potential of cardiac c-Kit+ progenitor cells via PI3K and MAPK signaling pathways.
Sign Up to like & getrecommendations! Published in 2020 at "Future cardiology"
DOI: 10.2217/fca-2018-0049
Abstract: In recent years, several studies have investigated cell transplantation as an innovative strategy to restore cardiac function following heart failure. Previous studies have also shown cardiac progenitor cells as suitable candidates for cardiac cell therapy… read more here.
Keywords: progenitor cells; myocardial regeneration; pi3k mapk; regeneration potential ... See more keywords