Quadruple‐editing of the MAPK and PI3K pathways effectively blocks the progression of KRAS‐mutated colorectal cancer cells
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DOI: 10.1111/cas.15049
Abstract: Mutated KRAS promotes the activation of the MAPK pathway and the progression of colorectal cancer (CRC) cells. Aberrant activation of the PI3K pathway strongly attenuates the efficacy of MAPK suppression in KRAS‐mutated CRC. The development… read more here.
Keywords: kras mutated; crc cells; quadruple editing; mapk pi3k ... See more keywords