Processing-independent analysis (PIA): a method for quantitation of the total peptide-gene expression
Sign Up to like & getrecommendations! Published in 2021 at "Peptides"
DOI: 10.1016/j.peptides.2020.170427
Abstract: The translational product of protein-coding genes undergoes extensive posttranslational modifications. The modifications ensure an increased molecular and functional diversity at protein- and peptide-level. Prohormones are small pro-proteins that are expressed in many cell types, for… read more here.
Keywords: processing independent; analysis pia; pia method; pia ... See more keywords
Cytotoxic selectivity and apoptosis induction of piericidin A contributes potentially to its insecticidal effect against Mythimna separata (Lepidoptera: Noctuidae) larvae.
Sign Up to like & getrecommendations! Published in 2019 at "Pesticide biochemistry and physiology"
DOI: 10.1016/j.pestbp.2019.03.002
Abstract: Piericidin A (PIA), an active inhibitor of Complex I, is widely used in studies of the anti-bacterial and anti-disease competence, but its physiological and mechanistic effects have rarely been clearly defined in insect individual or… read more here.
Keywords: mythimna separata; pia; selectivity; effect ... See more keywords
Preparation and evaluation in vitro and in vivo of pristinamycin enteric-coated granules based on albumin nanoparticles
Sign Up to like & getrecommendations! Published in 2023 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2023.2182602
Abstract: Abstract Context The purpose of this study was to prepare enteric-coated particles based on albumin nanoparticles (NPs) using a mixture of PIA albumin NPs freeze-dried powder (PA-PIA) and PIIA albumin NPs freeze-dried powder (PA-PIIA) to… read more here.
Keywords: based albumin; piia; enteric coated; pristinamycin ... See more keywords
A non‐coding RNA from the intercellular adhesion (ica) locus of Staphylococcus epidermidis controls polysaccharide intercellular adhesion (PIA)‐mediated biofilm formation
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Microbiology"
DOI: 10.1111/mmi.14238
Abstract: Polysaccharide intercellular adhesin (PIA)‐associated biofilm formation is mediated by the intercellular adhesin (ica) locus and represents a major pathomechanism of Staphylococcus epidermidis. Here, we report on a novel long non‐coding (nc)RNA, named IcaZ, which is… read more here.
Keywords: polysaccharide intercellular; adhesion; pia; ica ... See more keywords
Abstract 3727: Plasma inhibitory activity (PIA) is a possible pharmacodynamic marker for clinical development of a next generation pan-TRK inhibitor, ONO-5390556
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-3727
Abstract: Background: Colorectal cancer and Mammary analogue secretory carcinoma harboring Neurotrophic tyrosine receptor kinase (NTRK/TRK) gene rearrangements developed resistance to Entrectinib, ALK/ROS/TRK inhibitor. We previously demonstrated that the next generation pan-TRK inhibitor,ONO-5390556 may potently overcome Entrectinib-resistance… read more here.
Keywords: ono 5390556; inhibition trk; trk inhibitor; pia ... See more keywords
Molecularly Targeted Photothermal Ablation of Epidermal Growth Factor Receptor-Expressing Cancer Cells with a Polypyrrole–Iron Oxide–Afatinib Nanocomposite
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14205043
Abstract: Simple Summary In this manuscript, we describe the design and synthesis of a nanocomposite containing afatinib, polypyrrole, and iron oxide (PIA-NC) to molecularly target epidermal growth factor receptor (EGFR)-overexpressing cancer cells for photothermal conversion. In… read more here.
Keywords: cancer; cancer cells; nir ptt; pia ... See more keywords