Brain macrophages and pial fibroblasts promote inflammation in a hypomyelination model
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DOI: 10.1186/s40478-025-02063-3
Abstract: Many neurological diseases remain difficult to treat, necessitating further elucidation of their pathogenesis. Conditional inactivation of Pdgfra in Nestin-expressing cells leads to the depletion of platelet-derived growth factor receptor-alpha+ (PDGFRα+) oligodendroglial lineage cells responsible for… read more here.
Keywords: brain macrophages; pial fibroblasts; hypomyelination; inflammation ... See more keywords