Structure-Activity Relationship for the Picolinamide Antibacterials that Selectively Target Clostridioides difficile.
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DOI: 10.1021/acsmedchemlett.1c00135
Abstract: Clostridioides difficile is a leading health threat. This pathogen initiates intestinal infections during gut microbiota dysbiosis caused by oral administration of antibiotics. C. difficile is difficult to eradicate due to its ability to form spores,… read more here.
Keywords: difficile; clostridioides difficile; selectively target; picolinamide antibacterials ... See more keywords