Articles with "picoliter sample" as a keyword



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Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes

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Published in 2022 at "eLife"

DOI: 10.7554/elife.72629

Abstract: Cryogenic electron microscopy has become an essential tool for structure determination of biological macromolecules. In practice, the difficulty to reliably prepare samples with uniform ice thickness still represents a barrier for routine high-resolution imaging and… read more here.

Keywords: structure; sample volumes; structure determination; picoliter sample ... See more keywords